Giants vs Cardinals Prediction 25 September 2025

    San Francisco Giants
    San Francisco Giants
    St. Louis Cardinals
    St. Louis Cardinals
    4
    3
    0
    1
    1
    1
    0
    0
    0
    1
    -
    0
    0
    2
    0
    0
    0
    0
    1
    -

    In the MLB regular season, Oracle Park in San Francisco will host a clash between the hometown Giants and the visiting St. Louis Cardinals. Both teams are vying for a playoff spot, adding extra significance to this matchup. Considering the visitors' winning streak and the home team's recent losses, the game promises to be a tense affair.

    Head-to-Head

    The upcoming clash between the rivals promises to be thrilling. Their last encounter on September 24 ended with a dramatic victory for the Cardinals, who edged out a 9-8 win. Historically, the San Francisco Giants hold the upper hand with 79 victories, 55 of which have come on home turf. Meanwhile, the St. Louis Cardinals have claimed 68 wins, showcasing strong performances on the road with 41 victories. It's interesting to note the run statistics: the home team typically averages around 4.27 runs per game, while the visitors trail slightly, averaging 3.91 runs per match.

    Head-to-head statistics Giants - Cardinals

    53%
    80 Wins
    45%
    68 Wins
    25.09.25
    MLB
    San Francisco Giants
    San Francisco Giants
    St. Louis Cardinals
    St. Louis Cardinals
    4
    3
    0
    0
    1
    0
    1
    2
    1
    0
    0
    0
    0
    0
    0
    0
    1
    1
    24.09.25
    MLB
    San Francisco Giants
    San Francisco Giants
    St. Louis Cardinals
    St. Louis Cardinals
    8
    9
    0
    3
    0
    0
    5
    0
    0
    0
    2
    0
    1
    0
    0
    4
    0
    0
    0
    2
    23.09.25
    MLB
    San Francisco Giants
    San Francisco Giants
    St. Louis Cardinals
    St. Louis Cardinals
    5
    6
    1
    0
    0
    0
    0
    1
    3
    1
    1
    4
    0
    0
    0
    0
    0
    0
    07.09.25
    MLB
    St. Louis Cardinals
    St. Louis Cardinals
    San Francisco Giants
    San Francisco Giants
    4
    3
    0
    0
    0
    0
    0
    0
    0
    0
    4
    0
    0
    3
    0
    0
    0
    0
    06.09.25
    MLB
    St. Louis Cardinals
    St. Louis Cardinals
    San Francisco Giants
    San Francisco Giants
    3
    2
    0
    0
    0
    0
    0
    0
    0
    2
    0
    0
    0
    0
    0
    0
    0
    0
    3
    0
    Empty
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    San Francisco Giants Team Overview

    The San Francisco Giants are going through a challenging stretch. Over their last 10 games, they've managed to secure just two victories, with a four-game home losing streak adding to their woes. Their average runs per game stand at just 3.8, which is below their season average. The significance of the upcoming game is undeniable: they need a win to climb the standings and break out of this prolonged slump.

    Match Results: San Francisco Giants

    04.09.26
    major league baseball
    New York Mets
    New York Mets
    San Francisco Giants
    San Francisco Giants
    10
    6
    3
    0
    4
    0
    0
    2
    0
    0
    0
    0
    2
    0
    0
    1
    1
    3
    L
    03.09.26
    major league baseball
    Pittsburgh Pirates
    Pittsburgh Pirates
    San Francisco Giants
    San Francisco Giants
    5
    2
    2
    0
    0
    0
    0
    0
    0
    0
    0
    0
    2
    0
    0
    2
    1
    0
    L
    02.09.26
    major league baseball
    Pittsburgh Pirates
    Pittsburgh Pirates
    San Francisco Giants
    San Francisco Giants
    4
    5
    0
    1
    0
    0
    0
    0
    1
    0
    0
    2
    0
    0
    1
    0
    1
    0
    0
    0
    1
    2
    W
    01.09.26
    major league baseball
    Pittsburgh Pirates
    Pittsburgh Pirates
    San Francisco Giants
    San Francisco Giants
    13
    12
    2
    0
    0
    5
    9
    0
    0
    0
    0
    0
    0
    2
    1
    0
    0
    5
    1
    0
    L
    31.08.26
    major league baseball
    Atlanta Braves
    Atlanta Braves
    San Francisco Giants
    San Francisco Giants
    3
    7
    1
    1
    1
    0
    0
    0
    0
    0
    1
    1
    0
    4
    0
    0
    0
    0
    0
    1
    W
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    St. Louis Cardinals Team Overview

    St. Louis Cardinals, on the other hand, are on an upswing: six wins in their last 10 games indicate the team's strong form. The visitors consistently score over five runs per game and show confident performances on the road, as evidenced by two recent victories over the Giants. This outcome suggests that the team is ready to extend their successful streak and solidify their place among the league's frontrunners.

    Match Results: St. Louis Cardinals

    05.09.26
    major league baseball
    Colorado Rockies
    Colorado Rockies
    St. Louis Cardinals
    St. Louis Cardinals
    6
    7
    1
    0
    0
    2
    0
    0
    0
    0
    0
    2
    4
    0
    1
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    0
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    3
    W
    04.09.26
    major league baseball
    Los Angeles Dodgers
    Los Angeles Dodgers
    St. Louis Cardinals
    St. Louis Cardinals
    3
    2
    0
    1
    0
    0
    0
    1
    0
    0
    1
    0
    0
    0
    0
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    0
    0
    2
    0
    L
    03.09.26
    major league baseball
    Los Angeles Dodgers
    Los Angeles Dodgers
    St. Louis Cardinals
    St. Louis Cardinals
    6
    8
    3
    0
    0
    0
    0
    0
    0
    0
    0
    0
    2
    2
    0
    2
    0
    1
    0
    0
    1
    3
    W
    02.09.26
    major league baseball
    Los Angeles Dodgers
    Los Angeles Dodgers
    St. Louis Cardinals
    St. Louis Cardinals
    8
    13
    0
    0
    0
    2
    3
    5
    0
    2
    1
    1
    0
    0
    1
    1
    0
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    3
    0
    W
    30.08.26
    major league baseball
    St. Louis Cardinals
    St. Louis Cardinals
    Pittsburgh Pirates
    Pittsburgh Pirates
    4
    5
    0
    0
    0
    2
    0
    1
    0
    0
    2
    1
    0
    0
    2
    1
    0
    0
    0
    0
    L
    Empty
    There are no events
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    ⭐ Editorial Prediction

    Considering the current form of both teams and their results in previous head-to-head encounters this season, the visitors seem to have the upper hand. They have been consistent both at home and on the road, while the hosts continue to struggle with scoring and defending their home turf. In this scenario, a St. Louis Cardinals win appears to be a solid bet, given their current form and motivation to secure their position as the regular season draws to a close.

    St. Louis Cardinals Win
    Bovada
    Place a bet+107
    Published: 24/09/2025, 09:18

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    Betting Tips: San Francisco Giants - St. Louis Cardinals

    San Francisco Giants have lost:
    san-francisco-giantsin last 4 home games (MLB).
    St. Louis Cardinals Win
    MyBookie
    -105
    Over 4.5 runs scored:
    san-francisco-giantsin 33 of last 35 San Francisco Giants games (MLB).
    san-francisco-giantsin last 15 San Francisco Giants home games (MLB).
    st-louis-cardinalsin last 23 St. Louis Cardinals away games (MLB).
    st-louis-cardinalsin 17 of last 18 St. Louis Cardinals games (MLB).
    Total Over (4,5)
    -526
    Under 11.5 runs scored:
    st-louis-cardinalsin 6 of last 7 St. Louis Cardinals games (MLB).
    Total Under (11,5)
    -526
    St. Louis Cardinals won with a +2.5 handicap:
    st-louis-cardinalsin 7 of last 8 away games (MLB).
    St. Louis Cardinals Handicap (+2,5)
    -
    View more facts