Padres vs Yankees Prediction 5 September 2026

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The main thing

    📡 The opening game of the series turned into a true pitchers’ duel, with San Diego edging out a 3-2 victory in 10 innings. Tonight’s matchup once again features two high-caliber left-handers, but the total is set at just 6.5-noticeably lower than usual for lineups with this much firepower. After a marathon Friday night contest, bullpen fatigue for key relievers could also come into play.

    Head-to-Head

    📊 Prior to this series, San Diego had managed just three wins in their last 10 games against the Yankees. Friday’s 3-2 result slightly improved their record, but this matchup has also seen much higher-scoring affairs in the past. While New York still hold the historical edge, that alone doesn’t guarantee a low-scoring contest this time around.

    Head-to-head statistics Padres - Yankees

    38%
    5 Wins
    62%
    8 Wins
    05.09.26
    major league baseball
    San Diego Padres
    San Diego Padres
    New York Yankees
    New York Yankees
    3
    2
    0
    0
    1
    0
    0
    1
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    2
    1
    07.05.25
    MLB
    New York Yankees
    New York Yankees
    San Diego Padres
    San Diego Padres
    4
    3
    0
    0
    0
    0
    0
    0
    0
    1
    0
    0
    0
    0
    1
    0
    2
    2
    0
    0
    1
    0
    06.05.25
    MLB
    New York Yankees
    New York Yankees
    San Diego Padres
    San Diego Padres
    12
    3
    0
    0
    0
    0
    0
    0
    2
    2
    0
    0
    0
    0
    10
    1
    0
    0
    05.05.25
    MLB
    New York Yankees
    New York Yankees
    San Diego Padres
    San Diego Padres
    3
    4
    0
    0
    0
    0
    2
    0
    0
    0
    0
    0
    1
    0
    0
    0
    0
    4
    0
    0
    26.05.24
    MLB
    San Diego Padres
    San Diego Padres
    New York Yankees
    New York Yankees
    5
    2
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    4
    1
    1
    0
    0
    0
    Empty
    There are no events
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    San Diego Padres Team Overview

    The Padres opened the series with a win, improving their record to 74-67. The team remains in the playoff hunt and consistently finds production from the heart of their lineup at home. Scoring five runs in the opener doesn’t fully showcase the offensive firepower these sides possess, especially after extra innings and late bullpen appearances came into play.

    Match Results: San Diego Padres

    05.09.26
    major league baseball
    San Diego Padres
    San Diego Padres
    New York Yankees
    New York Yankees
    3
    2
    0
    0
    1
    0
    0
    1
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    2
    1
    W
    02.09.26
    major league baseball
    Cincinnati Reds
    Cincinnati Reds
    San Diego Padres
    San Diego Padres
    7
    3
    0
    2
    4
    1
    0
    0
    0
    0
    0
    0
    1
    0
    2
    0
    0
    0
    L
    01.09.26
    major league baseball
    Cincinnati Reds
    Cincinnati Reds
    San Diego Padres
    San Diego Padres
    4
    3
    1
    1
    0
    0
    0
    0
    0
    0
    1
    1
    0
    0
    0
    0
    2
    0
    L
    31.08.26
    major league baseball
    Cincinnati Reds
    Cincinnati Reds
    San Diego Padres
    San Diego Padres
    0
    5
    0
    0
    0
    0
    0
    0
    0
    4
    0
    0
    0
    0
    0
    1
    0
    0
    0
    0
    W
    30.08.26
    major league baseball
    Tampa Bay Rays
    Tampa Bay Rays
    San Diego Padres
    San Diego Padres
    5
    4
    0
    0
    0
    0
    0
    0
    1
    2
    0
    0
    0
    0
    0
    1
    0
    0
    2
    0
    2
    1
    L
    Empty
    There are no events
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    New York Yankees Team Overview

    The Yankees, coming off Friday with an 80-61 record, remain one of the most potent offenses in the American League. Even at Petco Park, New York’s lineup is always a threat to swing the momentum with a couple of extra-base hits. With the total set at 6.5, it’s enough for one team to reach four runs while the other chips in with two or three for the over to hit.

    Match Results: New York Yankees

    05.09.26
    major league baseball
    San Diego Padres
    San Diego Padres
    New York Yankees
    New York Yankees
    3
    2
    0
    0
    1
    0
    0
    1
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    2
    1
    L
    03.09.26
    major league baseball
    Los Angeles Angels of Anaheim
    Los Angeles Angels of Anaheim
    New York Yankees
    New York Yankees
    3
    6
    0
    0
    0
    0
    0
    0
    0
    1
    0
    0
    0
    0
    1
    0
    0
    0
    0
    0
    2
    5
    W
    02.09.26
    major league baseball
    Los Angeles Angels of Anaheim
    Los Angeles Angels of Anaheim
    New York Yankees
    New York Yankees
    3
    7
    0
    3
    0
    0
    1
    1
    0
    0
    0
    0
    2
    0
    0
    0
    0
    2
    0
    1
    W
    01.09.26
    major league baseball
    Los Angeles Angels of Anaheim
    Los Angeles Angels of Anaheim
    New York Yankees
    New York Yankees
    10
    1
    0
    0
    0
    0
    1
    0
    3
    0
    2
    1
    1
    0
    0
    0
    3
    0
    L
    30.08.26
    major league baseball
    New York Yankees
    New York Yankees
    Boston Red Sox
    Boston Red Sox
    16
    1
    0
    0
    0
    0
    0
    0
    0
    0
    5
    0
    1
    0
    1
    0
    9
    1
    W
    Empty
    There are no events
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    ⚾ Starting Pitchers

    Robbie Ray gets the nod for San Diego, carrying a 3.08 ERA and a 1.29 WHIP into this matchup. While his overall numbers are solid, his control remains a concern-he’s issued 57 walks over 122.2 innings. Against the Yankees, extra free passes could quickly turn into costly runs with just one well-timed hit.

    Carlos Rodon enters with a 3.20 ERA and a 1.19 WHIP. The left-hander has walked 31 batters in 59 innings, so even in a strong campaign, he’s allowed plenty of baserunners. The Padres at home are well-equipped to capitalize on these opportunities better than most opponents.

    ⭐ Editor’s Prediction

    Both starting pitchers look reliable, but the 6.5-run line leaves plenty of room for the over even if neither starter collapses. Ray and Rodon both issue a fair number of walks, and each lineup has enough power to turn a couple of baserunners into a big inning. With Friday’s game going to extra innings, the top relievers from both bullpens have already seen action. A 4-3 scoreline would be enough to cash this pick, and that scenario seems entirely plausible given these rosters. We’re backing the over 6.5 total runs.

    Total Over (6,5)
    Published: 05/09/2026, 07:01
    Evgeny Lisin
    Evgeny Lisin
    Baseball expert
    48
    1
    57
    106 predictions
    Statistics for September 2026

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    Betting Tips: San Diego Padres - New York Yankees

    Under 8.5 runs scored:
    san-diego-padresnew-york-yankeesin 6 of last 7 San Diego Padres games against New York Yankees (MLB).
    Total Under (8,5)
    -143
    New York Yankees won with a +1.5 handicap:
    san-diego-padresnew-york-yankeesin 8 of last 9 games against San Diego Padres (MLB).
    new-york-yankeesin 7 of last 8 away games (MLB).
    New York Yankees Handicap (+1,5)
    -238
    San Diego Padres won with a +2.5 handicap:
    san-diego-padresin 15 of last 17 games (MLB).
    San Diego Padres Handicap (+2,5)
    -312
    San Diego Padres won with a +1.5 handicap:
    san-diego-padresin last 12 home games (MLB).
    San Diego Padres Handicap (+1,5)
    Bovada
    -185