Lazio vs Milan Prediction 12 September 2026
📢 One of the standout matches of the round takes place at the Stadio Olimpico, where Lazio host Milan. After a disappointing previous season, the Eagles have made a bright start to the new Serie A campaign, winning all three of their opening fixtures. The Rossoneri under their new coaching staff also look confident, picking up seven points from a possible nine. With both sides keen to maintain that momentum, this fixture promises to be a particularly interesting one.
🔁 This prediction is updated on match day. Keep an eye on the Latest News section.
Head-to-Head
📊 The two sides have met 50 times in recent years. Milan have the better record: 22 wins to Lazio's 15, with 13 draws. Last season they met three times, and every match ended 1-0. In the league they each won at home, while in the Coppa Italia Round of 16 it was Lazio who came out on top.
Head-to-head statistics Lazio - Milan

Lazio Rome Team Overview
🔵 Last season was a very poor one for Lazio - the club failed to qualify even for the Conference League. The new campaign has not started smoothly either, with the Eagles losing at home to Mantova 0-2 and going out of the Coppa Italia at the first hurdle. In the league, however, things are going well: Lazio are one of three sides who remain unbeaten after three rounds. The quality of the opposition they have faced makes that start look all the more impressive.
⚪ In the third round, Lazio travelled to a solid Udinese side and ground out a 2-1 win. In the first half the Romans looked noticeably weaker than their hosts, and they conceded shortly after the break as well. But that goal did not knock them back - if anything, it prompted a sharp response. Lazio increased their pressure significantly and ultimately turned the match around on merit. For the fans, the fact that the decisive goal came in the 88th minute was particularly pleasing, showing the team's fighting spirit.
Match Results: Lazio Rome

Milan Team Overview
🔴 Ruben Amorim took charge of Milan ahead of the new season. Many were sceptical about the appointment, but the first three rounds have suggested things are going reasonably well under the Portuguese. The Rossoneri beat Torino (2-1) and Venezia (2-0), then drew away at Juventus (1-1) last weekend. Given that fixture list, seven points from nine and a provisional fifth place represent a very decent return.
⚫ That run could easily have been a perfect nine points. Against Juventus, Milan took the lead on 68 minutes and held it until almost the very end, only to concede in stoppage time. On the other hand, the quality of their performance hardly merited even a point: over the 90 minutes they managed just 3 shots to Juventus's 14, lost the big-chance count 0-3, and the xG gap was enormous. So Milan really have little reason to be too disappointed with that draw.
Match Results: Milan
Latest news
Lazio Rome
❌ Lazio head into matchday four with several injury concerns. Nicolò Rovella is still recovering from a shin injury. Adam Marušić, Danilo Cataldi and Fisayo Dele-Bashiru are all expected to return around the end of September. On top of that, the availability of Luca Pellegrini and Patrick for the upcoming match remains in doubt.
🔁 Update - 12 September, 07:00 UTC:
- Lazio's ultras will continue their boycott of home matches in protest against club president Claudio Lotito. They will not attend the match against Milan, though they plan to show their support for the team before kick-off. Around 10,000 Milan supporters are expected to be in the stands, meaning Lazio will effectively be playing in an away atmosphere.
Milan
❌ Milan have just one absentee. Matteo Gabbia is recovering from an ankle injury.
Predicted Lineups:
📋 Predicted starting XI for Lazio: Mandas - Floriani, Doekhi, Provstgaard, Tavares - Frattesi, Belahyane, Taylor - Isaksen, Pinamonti, Zaccagni.
📋 Predicted starting XI for Milan: Maignan - Gila, De Winter, Pavlović - Chukwueze, Musah, Modrić, Estupiñán - Rabiot, Cisse, Ramos.
⚽️ Goals Prediction
Although Lazio have changed their head coach, the team's defensive solidity hasn't suffered as a result. They have conceded just one goal in three rounds, and their Greek goalkeeper has been keeping a very high standard. If Milan create as little going forward as they did against Juventus, the hosts should have little trouble keeping the Rossoneri at bay. On that basis, Milan Team Total - Under 1.5 at 1.55* looks a logical option.
🚩 Corners Prediction
For those who like betting on set-piece markets, Total Corners - Under 8.5 at 2* is worth considering. In 10 of Milan's last 11 Serie A matches, the two sides combined for no more than eight corners - a trend that stretches back to the end of last season. In the new campaign, the Rossoneri themselves haven't been winning corners all that frequently either, which makes this a reasonably grounded bet.
🟨 Yellow Cards Prediction
Both teams picked up a fair number of bookings in the opening rounds. Lazio's average is 2 yellow cards per match, while Milan's is slightly lower at 1.7. Given the status of this fixture as the standout game of the round, there should be plenty of intensity and physical contest on the pitch. Total Yellow Cards - Over 3.5 at 1.55* is worth considering.
🚀 Player Statistics Bet
Ahead of the season, Lazio signed Davide Frattesi on loan from Inter. Few would have expected the 26-year-old Italian to become the team's top scorer at the start of the campaign. The midfielder has scored three goals in three rounds, while Lazio as a whole have found the net just four times. Given that form, there is a case for taking a punt on Davide Frattesi to Score at 6.20*.
😱 Risky Bet
As already noted, all three head-to-head meetings last season ended with just one goal scored. A similar scenario is possible here, particularly given how low-scoring Lazio's matches have been at the start of this campaign. If both sides approach the game cautiously from the off, goals may be hard to come by. Total Goals - Under 1.5 at 3.30* is an interesting high-risk option.
🎯 Reliable Bet
Total Goals - Under 3.5 at 1.22* looks the more reliable option. Several trends point towards a low-scoring game. This bet has landed in 7 of the last 8 head-to-head meetings between Lazio and Milan. A similar picture emerges when looking at each team individually: it has come in in 10 of the Rossoneri's last 11 Serie A matches, and in 7 of Lazio's last 8 home games.
👀 If the Match Takes a Different Turn
Any game can go in an unexpected direction, and the Lazio-Milan match will be no exception. Both teams have made a good start to the new season and will clearly be keen not to end their unbeaten runs. If one side scores early, the game will almost certainly open up and the other team will need to push forward more. In that scenario, Total Goals - Over 2.5 at 2.35* starts to look more appealing.
*Odds are indicative and may vary across different bookmakers.
⭐️ Editorial Prediction
The bookmakers have Milan as favourites for this match, but that assessment is debatable. Lazio have looked no worse in terms of playing quality at the start of the season, and they will also have the backing of their home crowd in this fixture. It seems unlikely that either side will open up from the first minute and commit to an aggressive approach - recent head-to-head meetings have consistently been played in a cautious manner. Taking into account Lazio's tendency towards low-scoring outcomes as well, our main bet is Total Goals - Under 2.5. The expected score is 1-0.
