Lyon vs Manchester United Prediction 10 April 2025
🔊 The Europa League quarter-final clash between Lyon and Manchester United is full of intrigue. Both teams are in fine form, showcasing confident performances in recent matches. Lyon's attacking prowess at home is impressive, while Manchester United also maintain high scoring rates, frequently netting over 1.5 goals in Europa League fixtures. Interestingly, bookmakers see no clear favorite in this upcoming game, offering nearly equal odds.
Head-to-Head
The teams have not faced each other in official matches since 2008. Back then, a goal from Cristiano Ronaldo decided the two-legged tie in the Champions League Round of 16, with Manchester advancing and eventually winning the tournament.
Head-to-head statistics Lyon - Manchester United

Olympique Lyon Team Overview
⚪ Lyon are currently fifth in Ligue 1, fiercely competing for a Champions League spot, trailing Marseille by just 4 points. Throughout the season, they changed their head coach, with Paulo Fonseca now at the helm, although only for the Europa League. The Portuguese manager faces a nine-month domestic ban due to aggressive behavior towards a referee. Despite this setback, the club has decided to stick with him and has filed an appeal.
🔗 In European competitions, Lyon have been impressive, finishing sixth in the league stage. They confidently dispatched FCSB in the playoffs over two legs (7-1). Malik Fofana, Georges Mikautadze, and Ernest Nuamah each scored twice in this encounter.
📣 Following the victory over FCSB, Paulo Fonseca commented on his suspension: “The people who made this decision considered the broader situation in French football. I am the one paying the price. I have seen how similar situations have been handled in France before. The punishments were different. This is unjust.”
❌ Lyon face significant setbacks ahead of their clash with Manchester United. The scorers of four goals against FCSB are sidelined due to injuries. Malik Fofana has already missed two matches, and Ernest Nuamah tore his cruciate ligaments in the last Ligue 1 round. Duje Ćaleta-Car's participation is also doubtful, as he missed the squad for the last two matches due to injury.
Match Results: Olympique Lyon

Manchester United Team Overview
🔴 Ruben Amorim seems to have found something within his squad. While it might be premature to talk about a complete resurgence, there is undeniable progress. For instance, last weekend United held Manchester City to a draw in the derby (0-0), and they were arguably closer to clinching a victory at Old Trafford.
🔗 Despite this, United remain in the lower half of the league table, so all eyes are on the Europa League. The Red Devils can certainly be considered strong contenders for the tournament. In the Round of 16, they delivered what was perhaps their most impressive performance under Amorim, thrashing Real Sociedad 4-1. Bruno Fernandes was the star of the show with a hat-trick.
📣 Ruben Amorim praised the Portuguese playmaker’s impact on the team: “He can threaten from set-pieces, score penalties under pressure, and dictate play in the closing stages of matches. We need to help him win a trophy because he deserves it.”
❌ In the upcoming fixture, long-term absentees Amad Diallo, Jonny Evans, and Lisandro Martinez will not feature. However, Kobbie Mainoo, who has been sidelined for nearly two months due to injury, is nearing a return. Matthijs de Ligt missed the Manchester derby, so his participation in the upcoming match remains uncertain.
Match Results: Manchester United
Prediction on the outcome
Statistics: Olympique Lyon vs Manchester United
- number of matches played in the tournament: 8 vs 8;
- number of wins: 6 vs 6;
- win percentage: 60% vs 60%;
- number of losses: 1 vs 0;
- number of draws: 3 vs 4.
Last 10 matches:
- number of wins: 8 vs 3;
- number of losses: 2 vs 3;
- number of draws: 0 vs 4.
Prediction on the over/under
Statistics: Olympique Lyon vs Manchester United
- average total in the tournament: 3.2 vs 3.2;
- average total goals scored: 2.3 vs 2.1;
- average total in the 1st half: 0.8 vs 0.7;
- average total in the 2nd half: 1.5 vs 1.4;
- Olympique Lyon: average total at home in the tournament - 2;
- Manchester United: average total away in the tournament - 1.8;
- last 10 matches (average total): 2.9 (home - 3) vs 1.5 (away - 1.2).
- Over 2.5 goals scored in last 6 Olympique Lyon home games.
Prediction on corners
Olympique Lyon: Statistics
- season: average Over/Under in the tournament - 5.9; at home field - 6.6;
- last 10 matches: average Over/Under - 3.7; at home field - 3.33.
Manchester United: Statistics
- season: average Over/Under in the tournament - 6, away - 5.2;
- last 10 matches: average Over/Under - 5.2; away - 5.8.
Prediction on cards
Olympique Lyon: Statistics
- season: average Over/Under in the tournament - 2; at home - 1.8;
- last 10 matches: average Over/Under - 1.6; at home - 1.83.
Manchester United: Statistics
- season: average Over/Under in the tournament - 1.4, away - 1.4;
- last 10 matches: average Over/Under - 1.6; away - 1.2.
Prediction on BTTS
Statistics: Olympique Lyon vs Manchester United
- number of matches played in the tournament: 8 vs 8;
- number of matches in the season where both teams scored (BTTS): 6 vs 8;
- number of BTS matches for Olympique Lyon at home - 2 (40%);
- number of BTS matches for Manchester United away - 4 (80%).
Last 10 matches:
- number of BTTS matches: 7 vs 6;
- BTTS matches for Olympique Lyon at home - 4 (67%);
- BTTS matches for Manchester United away - 2 (40%).
Editorial Prediction
The match promises to be filled with scoring opportunities, considering the current form of both teams, who have been prolific in this season's Europa League campaign. A well-founded betting option appears to be over 2.5 goals, which has hit in Lyon's last six home matches.