Padres vs Diamondbacks Prediction 27 September 2026

Details
Key points
    San Diego Padres
    San Diego Padres
    Arizona Diamondbacks
    Arizona Diamondbacks
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    📡 The opening two games of the series turned into an offensive shootout: Arizona cruised to an 11-4 win, while San Diego answered back with a 10-7 victory. The Diamondbacks saw their six-game winning streak snapped, but their bats stayed hot-18 runs scored over two days. For the series finale, the visitors will turn to Michael Soroka, who brings a 3.31 ERA to the mound, while the Padres had yet to announce their starting pitcher at the time of writing. Despite Saturday’s loss, Arizona can still count on a more settled starting rotation as they look to close out the series.

    Arizona and San Diego have split the last ten evenly after two high-scoring games in the series.

    📊 Over their last 10 meetings, the teams are dead even at 5 wins apiece. The current series is also tied 1-1: Arizona opened with an 11-4 victory, then San Diego responded with a 10-7 win. In five of those last 10 head-to-head clashes, the winning side has put up at least eight runs, so high-scoring innings and momentum swings are a common theme in this matchup. There’s no clear home-field advantage here, making the starting pitcher a crucial factor heading into Game 3.

    Head-to-head statistics Padres - Diamondbacks

    51%
    85 Wins
    49%
    81 Wins
    27.09.26
    major league baseball
    San Diego Padres
    San Diego Padres
    Arizona Diamondbacks
    Arizona Diamondbacks
    9
    4
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    0
    1
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    1
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    1
    3
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    0
    27.09.26
    major league baseball
    San Diego Padres
    San Diego Padres
    Arizona Diamondbacks
    Arizona Diamondbacks
    10
    7
    1
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    1
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    1
    3
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    2
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    2
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    0
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    26.09.26
    major league baseball
    San Diego Padres
    San Diego Padres
    Arizona Diamondbacks
    Arizona Diamondbacks
    4
    11
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    07.08.26
    major league baseball
    Arizona Diamondbacks
    Arizona Diamondbacks
    San Diego Padres
    San Diego Padres
    1
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    0
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    1
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    0
    06.08.26
    major league baseball
    Arizona Diamondbacks
    Arizona Diamondbacks
    San Diego Padres
    San Diego Padres
    10
    4
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    6
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    Empty
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    The Padres answered with a ten-run outburst, but once again turned to their relievers too early.

    The Padres have improved their record to 90-71 and boast a 50-30 mark at home. After a rough 4-11 stretch, they bounced back in style with 10 runs on 13 hits, steadily building their lead from the third through the sixth inning. On average, San Diego score 4.43 runs per game while allowing 4.20. Their home form remains their biggest asset, and Saturday’s performance highlighted just how dangerous their lineup can be when the opposing starter fails to go deep into the game.

    Match Results: San Diego Padres

    27.09.26
    major league baseball
    San Diego Padres
    San Diego Padres
    Arizona Diamondbacks
    Arizona Diamondbacks
    9
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    W
    27.09.26
    major league baseball
    San Diego Padres
    San Diego Padres
    Arizona Diamondbacks
    Arizona Diamondbacks
    10
    7
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    W
    26.09.26
    major league baseball
    San Diego Padres
    San Diego Padres
    Arizona Diamondbacks
    Arizona Diamondbacks
    4
    11
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    L
    25.09.26
    major league baseball
    Los Angeles Dodgers
    Los Angeles Dodgers
    San Diego Padres
    San Diego Padres
    2
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    W
    24.09.26
    major league baseball
    Los Angeles Dodgers
    Los Angeles Dodgers
    San Diego Padres
    San Diego Padres
    1
    5
    0
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    0
    0
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    Empty
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    The Diamondbacks keep their offense firing and bring in Soroka, who boasts a 3.31 ERA.

    Arizona are 86-75 overall and 6-4 over their last ten games. Saturday’s loss snapped a lengthy winning streak, but their offense remains potent-they put up seven runs just a day after scoring eleven. Across two games in San Diego, the Diamondbacks tallied 18 runs on 18 hits. They’re averaging 4.57 runs per game this season, and their 41-39 record on the road shows they maintain much of their effectiveness away from home.

    Match Results: Arizona Diamondbacks

    27.09.26
    major league baseball
    San Diego Padres
    San Diego Padres
    Arizona Diamondbacks
    Arizona Diamondbacks
    9
    4
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    L
    27.09.26
    major league baseball
    San Diego Padres
    San Diego Padres
    Arizona Diamondbacks
    Arizona Diamondbacks
    10
    7
    1
    0
    0
    1
    2
    1
    3
    2
    2
    0
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    0
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    L
    26.09.26
    major league baseball
    San Diego Padres
    San Diego Padres
    Arizona Diamondbacks
    Arizona Diamondbacks
    4
    11
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    3
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    1
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    1
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    1
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    W
    24.09.26
    major league baseball
    Colorado Rockies
    Colorado Rockies
    Arizona Diamondbacks
    Arizona Diamondbacks
    8
    12
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    24.09.26
    major league baseball
    Colorado Rockies
    Colorado Rockies
    Arizona Diamondbacks
    Arizona Diamondbacks
    3
    5
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    W
    Empty
    There are no events
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    ⚾ Starting Pitchers

    As of the latest update, San Diego have yet to officially announce their starting pitcher. With Walker Buehler limited to just 3.2 innings on Saturday, the bullpen had to shoulder a heavy workload in what turned out to be a high-scoring contest. That uncertainty surrounding Sunday’s starter becomes especially significant given Arizona’s explosive offense, which has racked up 18 runs over the past two games.

    Michael Soroka gets the nod for Arizona, carrying a 9-5 record, a 3.31 ERA, and 110 strikeouts into this matchup. He offers a much more reliable option compared to San Diego’s brief outing on Saturday. In his most recent start on September 22, Soroka went seven strong innings to help the team secure a 7-2 victory. For the Diamondbacks, his ability to eat up innings is crucial after surrendering 10 runs in the previous game.

    ⭐ Editorial Prediction

    San Diego have been formidable at home and just put up a ten-run response, so this pick certainly carries some risk. However, even in defeat, Arizona’s bats kept producing, pushing their tally to 18 runs across the first two games of the series. The last 10 head-to-head meetings are split 5-5, meaning there’s no clear systemic edge for the Padres in this matchup. The key variable in Game 3 is Soroka, who brings a 3.31 ERA for the visitors, while the Padres’ starter remains unconfirmed. If the right-hander can give Arizona some length early, the Diamondbacks’ current offensive form should provide enough support to answer Saturday’s 7-10 result. Our editorial pick: Arizona Diamondbacks to win.

    Arizona Diamondbacks to Win
    MyBookie
    Place a bet-123
    Published: 27/09/2026, 07:08
    Evgeny Lisin
    Evgeny Lisin
    Baseball expert
    270
    1
    241
    512 predictions
    Statistics for September 2026

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    Betting Tips: San Diego Padres - Arizona Diamondbacks

    Arizona Diamondbacks have won:
    arizona-diamondbacksin 6 of last 7 games (MLB).
    Arizona Diamondbacks to Win
    Bovada
    -154
    San Diego Padres have won:
    san-diego-padresin 8 of last 9 home games (MLB).
    San Diego Padres to Win
    MyBookie
    +131
    Over 6.5 runs scored:
    san-diego-padresin 15 of last 17 San Diego Padres games (MLB).
    Total Over (6,5)
    -222
    San Diego Padres have scored over 3.5 runs:
    san-diego-padresin 9 of last 10 games (MLB).
    san-diego-padresin last 7 home games (MLB).
    San Diego Padres Total Over (3,5)
    +100
    View more facts