Padres vs Diamondbacks Prediction 26 September 2026

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    San Diego Padres
    San Diego Padres
    Arizona Diamondbacks
    Arizona Diamondbacks
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    📡 San Diego head into the final weekend of the regular season as one of the hottest clubs in the league. The Padres have taken nine of their last ten games and boast a 46-29 record at home. Arizona are also enjoying a strong run-going 6-4 over their most recent ten-so this matchup is far from a walkover. Casey Mize and Brandon Pfaadt are set to start on the mound, but with both teams in good form, current momentum could prove more decisive than the pitchers’ season-long stats.

    San Diego have won six out of their last ten games and consistently rack up big scores against Arizona’s pitching.

    📊 San Diego have claimed victory in six of the last ten head-to-head clashes. This season, the Padres have already beaten Arizona 6-4, 4-1, 10-4, 9-4, and 5-1, with three of those five wins coming by at least a four-run margin. At Petco Park, San Diego have taken two of four summer matchups, including a commanding 10-4 result.

    Head-to-head statistics Padres - Diamondbacks

    51%
    84 Wins
    49%
    81 Wins
    27.09.26
    major league baseball
    San Diego Padres
    San Diego Padres
    Arizona Diamondbacks
    Arizona Diamondbacks
    10
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    1
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    0
    1
    2
    1
    3
    2
    2
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    2
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    26.09.26
    major league baseball
    San Diego Padres
    San Diego Padres
    Arizona Diamondbacks
    Arizona Diamondbacks
    4
    11
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    3
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    1
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    3
    1
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    0
    0
    07.08.26
    major league baseball
    Arizona Diamondbacks
    Arizona Diamondbacks
    San Diego Padres
    San Diego Padres
    1
    5
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    1
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    0
    1
    2
    0
    0
    0
    0
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    0
    06.08.26
    major league baseball
    Arizona Diamondbacks
    Arizona Diamondbacks
    San Diego Padres
    San Diego Padres
    10
    4
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    0
    0
    0
    2
    0
    6
    0
    0
    0
    0
    0
    0
    0
    2
    0
    05.08.26
    major league baseball
    Arizona Diamondbacks
    Arizona Diamondbacks
    San Diego Padres
    San Diego Padres
    4
    9
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    3
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    3
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    4
    1
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    The Padres head into the final weekend having won nine of their last ten games.

    The Padres are enjoying their best offensive stretch of the season. Just a few days ago, they strung together three straight games with at least eight runs and now head into the decisive phase of the wild card race with hardly any setbacks. Fernando Tatis Jr., Jackson Merrill, and Xander Bogaerts are all delivering at the plate, and San Diego have looked significantly more consistent at home than on the road for most of the year.

    Match Results: San Diego Padres

    27.09.26
    major league baseball
    San Diego Padres
    San Diego Padres
    Arizona Diamondbacks
    Arizona Diamondbacks
    10
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    W
    26.09.26
    major league baseball
    San Diego Padres
    San Diego Padres
    Arizona Diamondbacks
    Arizona Diamondbacks
    4
    11
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    L
    25.09.26
    major league baseball
    Los Angeles Dodgers
    Los Angeles Dodgers
    San Diego Padres
    San Diego Padres
    2
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    W
    24.09.26
    major league baseball
    Los Angeles Dodgers
    Los Angeles Dodgers
    San Diego Padres
    San Diego Padres
    1
    5
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    W
    23.09.26
    major league baseball
    Los Angeles Dodgers
    Los Angeles Dodgers
    San Diego Padres
    San Diego Padres
    7
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    4
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    L
    Empty
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    Faadt is capable of keeping things under control, but September has already seen him suffer a major setback.

    The Diamondbacks have also picked up momentum in September, remaining a threat thanks to their lineup depth. Over their last ten games, they boast a solid 6-4 record, though their performance on the road has been noticeably weaker than at home this season. In their series against San Diego, Arizona have already shown they can win with strong pitching, but when the game opens up, the advantage has often swung toward the Padres’ more explosive offense.

    Match Results: Arizona Diamondbacks

    27.09.26
    major league baseball
    San Diego Padres
    San Diego Padres
    Arizona Diamondbacks
    Arizona Diamondbacks
    10
    7
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    L
    26.09.26
    major league baseball
    San Diego Padres
    San Diego Padres
    Arizona Diamondbacks
    Arizona Diamondbacks
    4
    11
    0
    3
    2
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    W
    24.09.26
    major league baseball
    Colorado Rockies
    Colorado Rockies
    Arizona Diamondbacks
    Arizona Diamondbacks
    8
    12
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    6
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    4
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    W
    24.09.26
    major league baseball
    Colorado Rockies
    Colorado Rockies
    Arizona Diamondbacks
    Arizona Diamondbacks
    3
    5
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    W
    23.09.26
    major league baseball
    Colorado Rockies
    Colorado Rockies
    Arizona Diamondbacks
    Arizona Diamondbacks
    2
    7
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    Empty
    There are no events
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    ⚾ Starting Pitchers

    Casey Mize has been inconsistent throughout September, surrendering 14 earned runs over his last 17.2 innings across four starts. His most recent outing against Miami was particularly rough-he was tagged for five runs, five hits, and issued five walks in just three innings. Despite Mize’s struggles on the mound, San Diego have managed to win three of those four games, with their offense and bullpen stepping up to offset the shaky starts.

    Brandon Pfaadt enters with a 3.72 ERA and a 1.17 WHIP. In his three September starts, he’s allowed ten earned runs over 17.1 innings-giving up one to the Yankees, six to Texas, and three to Houston. Statistically, Pfaadt’s current form looks more reliable than Mize’s, but he hasn’t been immune to blow-up outings either.

    ⭐ Editor’s Prediction

    The opening pitching matchup doesn’t give San Diego a clear edge-Mize has struggled with early runs in September. Still, the Padres have thrived by overcoming rough starts and responding with firepower at the plate. They’ve won nine of their last ten games, boast a strong home record, and lead the recent head-to-head series 6-4. Faadt is also prone to shaky openings, and against this San Diego lineup, a single bad inning could swing the game. If the score is tied after five innings, the Padres’ bullpen and home-field advantage tip the scales further in their favor. We’re backing a San Diego Padres win.

    San Diego Padres to Win
    Bovada
    Place a bet-133
    Published: 25/09/2026, 05:38
    Evgeny Lisin
    Evgeny Lisin
    Baseball expert
    263
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    498 predictions
    Statistics for September 2026

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    Betting Tips: San Diego Padres - Arizona Diamondbacks

    San Diego Padres have won:
    san-diego-padresin 7 of last 8 games (MLB).
    San Diego Padres to Win
    Bovada
    -133
    Arizona Diamondbacks have won:
    arizona-diamondbacksin 7 of last 8 away games (MLB).
    arizona-diamondbacksin last 5 games (MLB).
    Arizona Diamondbacks to Win
    MyBookie
    +117
    Over 6.5 runs scored:
    san-diego-padresin 13 of last 15 San Diego Padres games (MLB).
    arizona-diamondbacksin last 6 Arizona Diamondbacks away games (MLB).
    Total Over (6,5)
    -167
    Under 9.5 runs scored:
    arizona-diamondbacksin 10 of last 11 Arizona Diamondbacks away games (MLB).
    Total Under (9,5)
    -278
    View more facts