Brewers vs Cardinals Prediction 26 September 2026

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Key points
    Milwaukee Brewers
    Milwaukee Brewers
    St. Louis Cardinals
    St. Louis Cardinals
    3
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    📡 Milwaukee are enjoying the best regular season in franchise history. Yesterday, the Brewers claimed an 8-4 win, pushing their record to 101-59 while once again showcasing their offensive depth-four decisive runs came in the eighth inning. St. Louis twice clawed their way back but ultimately couldn’t handle the late pressure. Tonight, the Cardinals send Quinn Mathews to the mound, while the hosts counter with Dustin May.

    Milwaukee have won nine of their last ten games and are firmly in control of this series.

    📊 Milwaukee have taken nine of their last ten meetings against St. Louis. Heading into yesterday's game, the Brewers already held an 8-2 advantage over that stretch, and this season’s home clashes have ended 5-1, 6-0, and 2-1 in their favor. This remains one of the Brewers’ most consistent matchups, with the hosts dominating both on the mound and at the plate.

    Head-to-head statistics Brewers - Cardinals

    52%
    91 Wins
    47%
    83 Wins
    27.09.26
    major league baseball
    Milwaukee Brewers
    Milwaukee Brewers
    St. Louis Cardinals
    St. Louis Cardinals
    6
    4
    3
    0
    0
    0
    2
    0
    1
    0
    0
    0
    0
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    4
    26.09.26
    major league baseball
    Milwaukee Brewers
    Milwaukee Brewers
    St. Louis Cardinals
    St. Louis Cardinals
    3
    2
    0
    0
    0
    1
    1
    1
    0
    0
    2
    0
    0
    0
    0
    0
    0
    0
    25.09.26
    major league baseball
    Milwaukee Brewers
    Milwaukee Brewers
    St. Louis Cardinals
    St. Louis Cardinals
    8
    4
    1
    0
    0
    0
    0
    0
    1
    1
    2
    0
    0
    0
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    3
    4
    0
    09.07.26
    major league baseball
    St. Louis Cardinals
    St. Louis Cardinals
    Milwaukee Brewers
    Milwaukee Brewers
    4
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    4
    1
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    3
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    1
    08.07.26
    major league baseball
    St. Louis Cardinals
    St. Louis Cardinals
    Milwaukee Brewers
    Milwaukee Brewers
    5
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    2
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    2
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    The Brewers once again sealed the game with a late four-run surge.

    The Brewers racked up 12 hits yesterday, with Brice Turang finishing the game with three hits and three RBIs. The team continues to excel in the late innings: after the score was tied at 4-4, the hosts immediately responded with a four-run eighth. Milwaukee have long secured their playoff spot, but they maintain their momentum and boast one of the league’s best home records.

    Match Results: Milwaukee Brewers

    27.09.26
    major league baseball
    Milwaukee Brewers
    Milwaukee Brewers
    St. Louis Cardinals
    St. Louis Cardinals
    6
    4
    3
    0
    0
    0
    2
    0
    1
    0
    0
    0
    0
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    0
    0
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    4
    W
    26.09.26
    major league baseball
    Milwaukee Brewers
    Milwaukee Brewers
    St. Louis Cardinals
    St. Louis Cardinals
    3
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    W
    25.09.26
    major league baseball
    Milwaukee Brewers
    Milwaukee Brewers
    St. Louis Cardinals
    St. Louis Cardinals
    8
    4
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    0
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    1
    2
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    0
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    3
    4
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    W
    24.09.26
    major league baseball
    Philadelphia Phillies
    Philadelphia Phillies
    Milwaukee Brewers
    Milwaukee Brewers
    1
    5
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    0
    0
    0
    0
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    0
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    3
    0
    1
    W
    23.09.26
    major league baseball
    Philadelphia Phillies
    Philadelphia Phillies
    Milwaukee Brewers
    Milwaukee Brewers
    1
    4
    0
    1
    1
    1
    0
    2
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    W
    Empty
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    Matthews remains in strong form, but the Cardinals once again fall short against Milwaukee’s superior squad depth.

    The Cardinals managed to tie the game in the seventh inning yesterday, but once again their offense failed to deliver in the late innings. Before arriving in Milwaukee, the team had scored just six runs over three games in Pittsburgh. This issue has been even more pronounced against the Brewers: in most losses during the current series, St. Louis haven’t been able to make up for runs allowed with their own bats.

    Match Results: St. Louis Cardinals

    27.09.26
    major league baseball
    Milwaukee Brewers
    Milwaukee Brewers
    St. Louis Cardinals
    St. Louis Cardinals
    6
    4
    3
    0
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    2
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    4
    L
    26.09.26
    major league baseball
    Milwaukee Brewers
    Milwaukee Brewers
    St. Louis Cardinals
    St. Louis Cardinals
    3
    2
    0
    0
    0
    1
    1
    1
    0
    0
    2
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    0
    0
    0
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    L
    25.09.26
    major league baseball
    Milwaukee Brewers
    Milwaukee Brewers
    St. Louis Cardinals
    St. Louis Cardinals
    8
    4
    1
    0
    0
    0
    0
    0
    1
    1
    2
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    0
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    L
    24.09.26
    major league baseball
    Pittsburgh Pirates
    Pittsburgh Pirates
    St. Louis Cardinals
    St. Louis Cardinals
    2
    1
    1
    1
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
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    L
    23.09.26
    major league baseball
    Pittsburgh Pirates
    Pittsburgh Pirates
    St. Louis Cardinals
    St. Louis Cardinals
    1
    5
    0
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    3
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    W
    Empty
    There are no events
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    ⚾ Starting Pitchers

    Dustin May enters with a 7-9 record and a 4.67 ERA. His last two outings were brief-he allowed two earned runs over two innings against Philadelphia and three over 2.1 frames versus Baltimore. However, back on September 11, he tossed six scoreless innings against Cincinnati, showing that his ceiling as a starter remains high.

    Quinn Mathews stands at 2-3 with a 3.65 ERA. He’s been impressive over his last four starts, giving up just one, two, one, and one earned run respectively. On September 14, he went 6.2 innings while racking up eight strikeouts. That kind of form is the key factor that could keep St. Louis competitive into the middle innings.

    ⭐ Editor’s Prediction

    Matthews is in solid form, so Milwaukee may not enjoy their usual early edge. Still, even a tight opening stretch leaves the Brewers in a favorable spot. They’ve claimed nine of the last ten head-to-head matchups, pulled off another late surge yesterday, and boast a much deeper bullpen for the later innings. Milwaukee have racked up 101 wins and consistently generate chances after the sixth inning. If May can keep St. Louis within three or four runs, the hosts should have plenty of time to engineer another late push. We’re backing a Milwaukee Brewers win.

    Milwaukee Brewers to Win
    Bovada
    Place a bet-189
    Published: 26/09/2026, 05:41
    Evgeny Lisin
    Evgeny Lisin
    Baseball expert
    276
    1
    243
    520 predictions
    Statistics for September 2026

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    Betting Tips: Milwaukee Brewers - St. Louis Cardinals

    Milwaukee Brewers have won:
    milwaukee-brewersst-louis-cardinalsin 9 of last 10 games against St. Louis Cardinals (MLB).
    milwaukee-brewersst-louis-cardinalsin 7 of last 8 home games against St. Louis Cardinals (MLB).
    milwaukee-brewersin 6 of last 7 games (MLB).
    St. Louis Cardinals have lost:
    st-louis-cardinalsin 6 of last 7 away games (MLB).
    Milwaukee Brewers to Win
    MyBookie
    -189
    Over 5.5 runs scored:
    milwaukee-brewersst-louis-cardinalsin 11 of last 12 Milwaukee Brewers games against St. Louis Cardinals (MLB).
    Total Over (5,5)
    -294
    Over 6.5 runs scored:
    milwaukee-brewersin last 10 Milwaukee Brewers home games (MLB).
    Total Over (6,5)
    -200
    Milwaukee Brewers won with a +1.5 handicap:
    milwaukee-brewersst-louis-cardinalsin 9 of last 10 games against St. Louis Cardinals (MLB).
    milwaukee-brewersst-louis-cardinalsin last 8 home games against St. Louis Cardinals (MLB).
    milwaukee-brewersin last 7 home games (MLB).
    milwaukee-brewersin 6 of last 7 games (MLB).
    Milwaukee Brewers Handicap (+1,5)
    -370
    View more facts