Santos Laguna vs San Luis Prediction 21 September 2025
⚡️ The upcoming clash between Santos Laguna and San Luis promises to be an intriguing encounter as both teams aim to climb the league standings. Both sides have shown inconsistent form: the hosts have secured just one win in their last five matches, while the visitors alternate between victories and defeats. Read the prediction for this matchup below.
Head-to-Head
The last official match between the teams took place in March and ended with a score of 2-3. Here's a comparative breakdown of that encounter (Santos Laguna were the home side):
- possession: 41% vs 59%;
- corner kicks: 7 vs 3;
- fouls: 13 vs 14;
- yellow cards: 0 vs 2;
- shots on target: 5 vs 3.
📊Statistical preview of the official encounters between Santos Laguna and San Luis:
- 12 matches played;
- home wins - 6, away wins - 4, draws - 2;
- goals scored - 20 for Santos Laguna, 16 for San Luis;
- average first-half total - 1.42, second-half - 1.58;
- average total goals per match - 3.
Head-to-head statistics Santos Laguna - San Luis

Santos Laguna Team Overview
The last official match was part of the Liga MX tournament, with Atlas as the home team and Santos Laguna as the visitors. The match concluded with a 2-2 draw.
The game statistics are as follows (Santos Laguna vs Atlas):
- possession percentage: 64% vs 36%;
- corner kicks: 11 vs 4;
- fouls: 13 vs 18;
- yellow cards: 5 vs 5;
- shots on target: 8 vs 3.
Santos Laguna are going through a rough patch at the moment. The team have managed just one win in their last ten matches and are struggling defensively, conceding an average of two goals per game. Their most recent victory came on home turf, offering hope to the "Guerreros" fans for success in the upcoming match.
Match Results: Santos Laguna

San Luis Team Overview
The most recent official match for the current visitors took place in the Liga MX tournament (home team - San Luis, visitors - Tijuana). The match ended in a 1-1 draw.
Here are the game statistics (San Luis vs Tijuana):
- possession: 49% vs 51%;
- corner kicks: 3 vs 5;
- fouls: 12 vs 16;
- yellow cards: 2 vs 1;
- shots on target: 3 vs 6.
San Luis are also struggling to find consistent form, having secured just three wins in their last ten outings. The team continues to search for their optimal playing style. Defensively, they tend to make mistakes, conceding an average of 1.75 goals per game. Despite these challenges, their attack remains fairly effective, averaging just over one goal per match.
Match Results: San Luis
Outcome Prediction
Head-to-Head Matches:
- Number of encounters - 12;
- Home victories - 6, away victories - 4, draws - 2.
Statistics: Santos Laguna vs San Luis
- Matches played in the tournament: 8 vs 8;
- Wins: 2 vs 2;
- Win percentage: 25% vs 25%;
- Losses: 5 vs 5;
- Draws: 1 vs 1.
Last 10 Matches:
- Wins: 1 vs 3;
- Losses: 8 vs 6;
- Draws: 1 vs 1.
- Santos Laguna have failed to win in 9 of their last 10 matches.
Total Goals Prediction
Head-to-Head Matches:
- Today's home team averages - 1.67 goals, away team - 1.33;
- Average total goals in head-to-head matches - 3;
- Both teams scored: overall - 7 times; at the home team's field - 3 times.
Statistics: Santos Laguna vs San Luis
- Average tournament total: 3 vs 3.13;
- Average goals scored: 1.38 vs 1.38;
- Average first-half total: 0.88 vs 0.38;
- Average second-half total: 0.5 vs 1;
- Santos Laguna: average home total in the tournament - 1.5;
- San Luis: average away total in the tournament - 2;
- Last 10 matches (average total): 1 (home - 1) vs 1.4 (away - 1.83).
- Santos Laguna have scored less than 2.5 goals in the last 5 head-to-head matches against this team (Liga MX).
- Santos Laguna have scored less than 2.5 goals in 37 of their last 38 matches.
- Santos Laguna have scored less than 2.5 goals in 34 of their last 35 matches (Liga MX).
- Santos Laguna have scored less than 2.5 goals at home in 17 of their last 18 matches (Liga MX).
Corners Prediction
Head-to-Head Matches
- Average total corners in head-to-head matches - 9.66 (6.08 for the home team and 3.58 for the visitors);
- Average total corners at the home field - 10.34 (6.67 for the home team and 3.67 for the visitors).
Santos Laguna: Statistics
- Season: average tournament total - 4; at home - 2.75;
- Last 10 matches: average total - 4.1; at home - 3.33.
San Luis: Statistics
- Season: average tournament total - 4.5, away - 6;
- Last 10 matches: average total - 4.1; away - 4.83.
- San Luis have delivered more than 4.5 corners in five consecutive away matches (Liga MX).
Cards Prediction
Head-to-Head Matches
- Average total yellow cards in head-to-head matches - 3.34 (1.67 for the home team and 1.67 for the visitors);
- Average total yellow cards at the home field - 3.34 (1.17 for the home team and 2.17 for the visitors).
Santos Laguna: Statistics
- Season: average tournament total - 2.5; at home - 2.75;
- Last 10 matches: average total - 2.9; at home - 3.
San Luis: Statistics
- Season: average tournament total - 2.5, away - 2.5;
- Last 10 matches: average total - 2.5; away - 2.5.
Both Teams to Score Prediction
Head-to-Head Matches:
- Total encounters - 12;
- Both teams have scored overall - 7 times;
- At the home team's field - 3 times.
Statistics: Santos Laguna vs San Luis
- Total matches played in the tournament: 8 vs 8;
- Total season matches with both teams scoring (BTTS): 4 vs 5;
- Santos Laguna's BTTS at home - 1 (25%);
- San Luis' BTTS away - 2 (50%).
Last 10 Matches:
- Total BTTS matches: 6 vs 6;
- Santos Laguna's BTTS at home - 1 (33%);
- San Luis' BTTS away - 3 (50%).
⭐ Editorial Prediction
Given the current form of both sides and the outcomes of their recent encounters (particularly Santos Laguna's 2-3 defeat), we can anticipate a tense clash with plenty of goal-scoring opportunities for both teams. With the trend showing Santos struggling to secure victories in most games this season, and considering the recent defensive and attacking performances of the visitors, betting on both teams to score seems like a well-founded prediction for this match. The projected scoreline is 1-1.