Roma vs Inter Prediction 19 September 2026
📢 All eyes this weekend will be on the meeting between Roma and Inter. Gian Piero Gasperini's side have been excellent in the opening four rounds, winning all four matches. The reigning Italian champions have started just as well - Inter are also yet to drop a point. Notably, Roma and Inter are the only two Serie A sides who have not yet lost any points. After this fixture, at least one of those runs will come to an end, which only adds to the intrigue surrounding the fifth-round match at the Stadio Olimpico.
🔁 This prediction is updated on the day of the match. Keep an eye on the Latest News section.
Roma are finding it increasingly difficult to come up with answers against Inter.
📊 The two sides have met 44 times in recent years. Inter have a slight edge overall, with 18 wins to Roma's 12 and 14 draws. In more recent meetings that advantage has become more pronounced - Inter have won six of the last seven head-to-head matches. Last season the Nerazzurri took both fixtures: winning 1-0 in Rome and then putting on a far more high-scoring display at home, winning 5-2.
Head-to-head statistics Roma - Inter

Roma set a championship pace right from the opening rounds
🔴 Roma have not produced such a remarkable run of results at the start of a season for a long time. They have won all four of their opening Serie A matches, dominating some of them completely. Bookmakers have sharply cut their odds for the title - Roma are now considered the second favourites for the championship. The Champions League draw against Fenerbahçe last week slightly dented that picture, though a 1-1 in Istanbul is still a very good result in its own right.
🟡 In the previous Serie A round, Roma travelled to Torino, a side who tend to make life difficult for opponents. Roma were unfazed and looked very strong against them, holding roughly double the advantage across almost all the key statistical metrics. A 2-0 win looks entirely deserved in that context. Donyell Malen deserves a particular mention - he has six goals in four rounds and currently leads the Serie A scoring charts.
Match Results: Roma

Inter get the job done, even when they go through rough patches.
🔵 The reigning Italian champions have also taken 12 points from their opening four games, though they currently sit second purely on goal difference. After just four rounds, though, the table is hardly worth obsessing over - what matters for Inter right now is simply continuing to pick up points and maintaining the pace they have set. Like Roma, the Nerazzurri's only slip came in the Champions League last week, though the circumstances were about as difficult as they come: away at Real Madrid. A 1-2 defeat in those conditions is far from a disaster.
⚫ In the previous Serie A round, Inter were involved in a wild game at home against Udinese, winning 5-3. As in their recent match against Napoli, the Milanese side put themselves in an uncomfortable position and were again forced to come from 2-0 down. This time it was the opening stages that went badly wrong - by the 16th minute the Nerazzurri were already two goals behind. But from there, Cristian Chivu's side turned the game completely on its head and scored five consecutive goals. Only late on did Inter lose their focus slightly, conceding a third that had no bearing on the result. The statistics backed up the win convincingly: 27-6 in shots, 8-3 in clear-cut chances, and 2.83-0.76 in xG.
Match Results: Inter Milano
Latest news
Roma
✅ Roma have no injury or suspension concerns ahead of the fifth matchday and go into the game with a fully fit squad.
Inter Milano
❌ Inter have three injury concerns. Djed Spence is continuing his recovery from a shin injury but has returned to training. John Stones is out with a thigh injury, and Hakan Çalhanoğlu is sidelined with a groin injury. Both are expected to return around mid-October.
🔁 Update - 19 September, 12:57 UTC:
- In the early hours of 19 September 2026, Sandro Mazzola - one of the greatest players in Inter's history - passed away in Milan at the age of 83. Both teams will wear black armbands, and a minute's silence will be held before the match. It is also the 100th anniversary of the Nerazzurri's home ground, the Giuseppe Meazza. The upcoming match therefore carries enormous significance for the visitors - not only in terms of the standings, but emotionally as well.
Predicted Lineups
📋 Roma predicted starting XI: Svilar - Mancini, Balerdi, Hermoso - Lulli, Koné, Cristante, Wesley - Dybala, Soulé, Malen
📋 Inter predicted starting XI: Martínez - Bisseck, Akanji, Bastoni - Diouf, Barella, Zieliński, Jones, Dimarco - Thuram, Lautaro
⚽️ Goals Prediction
Roma's attack, which hit its stride last season, has continued at the same level - the team have scored at least two goals in each of their last 9 consecutive Serie A matches. Given Inter's less-than-solid defensive displays and frequent defensive lapses, a bet on Roma Team Total - Over 1.5 Goals at 2.15* looks like it could come in comfortably.
🚩 Corners Prediction
Roma rarely earn many corners in matches against Inter. In 9 of their last 10 Serie A head-to-head meetings, the Giallorossi took fewer than five corners. Yes, Roma have been putting up very high corner numbers at the start of this season, but the level of resistance here will be quite different. Inter are unlikely to allow the hosts to press around their penalty area as freely or as often, so Roma Team Total - Under 4.5 Corners at 1.90* looks an interesting option.
🟨 Yellow Cards Prediction
A top-of-the-table clash, enormous stakes, a fight for the provisional league lead - all of this creates the perfect conditions for a highly charged atmosphere. Neither side will want to give ground in such a fiercely contested match, which means plenty of physical duels and, as a result, a fair few bookings from the referee. The bet is Total Yellow Cards - Over 3.5 at 1.75*.
🚀 Player Statistic Bet
As already noted, Donyell Malen has not let up after a fantastic last season and continues to score just as regularly as before. In Serie A, he failed to get on the scoresheet only against Atalanta, though he still showed well in attack that day. In such an important match, Roma will surely be leaning heavily on their top scorer again, so a bet on Donyell Malen to Score at 2.09* is worth considering.
😱 Risky Bet
If you believe in the Dutchman, you can go a step further and back Donyell Malen to Score 2 or More Goals. This season he has already managed both a brace and a hat-trick. With Inter's defence as it is, he will likely have several chances, and the striker is also the team's designated penalty taker. The odds are quite attractive at 7.10*.
🎯 Safe Bet
If you are looking for a more reliable option, you can simply back Roma to Score at 1.22*. This bet has not let anyone down for some time - Roma have scored in 22 consecutive official matches. Inter, meanwhile, have kept a clean sheet in just one of their five matches this season, against Cagliari.
👀 If the Match Goes Off Script
Any game can go off script, and this one is no exception. Yes, Roma are very strong in attack, but they have not yet faced opposition of Inter's level. The Nerazzurri are not impressing defensively at the moment, but in such a significant match they may well draw on what they built last season. If the visitors repeatedly manage to neutralise Roma's attacks, it would be worth looking at Roma Team Total - Under 1.5 Goals at 1.75*.
*Odds are indicative and may vary across different bookmakers.
⭐️ Editorial Prediction
The bookmakers see no clear favourite for this match, which is understandable. Both sides have made a brilliant start to the season, have their own strengths, and are yet to drop a point. The attacking lines on both sides are particularly impressive: the hosts have scored 12 goals in four rounds, while the visitors have scored 13 - the two best tallies in the league. Both teams will be going for the win and a draw suits neither, so an open, end-to-end game is quite possible. We're backing Both Teams to Score - Yes, especially given that this bet has landed in 6 of Inter's last 7 matches. The expected score is 3-2.
