OFI vs Hoffenheim Prediction 17 September 2026
🔊 OFI and Hoffenheim will open their Europa League league phase campaigns with a match in Crete. The hosts come into the game in excellent form and have already beaten Olympiacos, while the German club only picked up their first win of the Bundesliga season in the third matchday. For OFI, this is a historic European match, and Hoffenheim will look to justify their status as favourites through superior individual quality.
🔁 We will update this prediction as new information about the teams becomes available. Check back just before kick-off so you don't miss any important changes.
Head-to-Head
📊 OFI and Hoffenheim have never met in an official match before. The upcoming game will be their first ever meeting.
Head-to-head statistics OFI - Hoffenheim

OFI Team Overview
OFI come into their Europa League opener in good spirits. In the previous round of the Greek championship, Christos Kontis's side beat Olympiacos 1-0 away from home, with Kenan Kodro scoring the only goal. That victory was OFI's third in four opening Superliga matches.
Particularly significant is the fact that OFI already have experience of big occasions. Last season the club won the Greek Cup, beating PAOK in extra time, which earned them the chance to return to the main stage of European competition for the first time in a quarter of a century.
Hoffenheim have a fairly mobile attack and can punish defensive errors during transitions, so the hosts will need to be especially disciplined at the back. OFI's main advantage is home ground. In Crete the team are capable of playing with considerably more freedom, and the emotional atmosphere of their first European match at Pankritio should help the hosts cope with the pressure of facing the favourites.
Match Results: OFI

Hoffenheim Team Overview
Hoffenheim began the Bundesliga season with two defeats - 2-3 to Köln and 2-3 to Borussia Dortmund. In both matches, Christian Ilzer's side scored twice and remained in contention for a positive result until late on.
The third round brought a change. Hoffenheim beat Stuttgart 2-1 at home thanks to a brace from Adam Hložek, giving the club a timely boost just before the start of their European campaign. Scoring has been one of Hoffenheim's strengths so far: they have netted at least two goals in each of their three opening Bundesliga matches.
Last season Hoffenheim finished fifth in the Bundesliga - their best result since 2017/18 - and they return to European football no doubt hoping for a strong start. That said, the German club should not expect an easy ride. OFI have already shown they can beat more established opponents, and their victory over Olympiacos suggests the hosts are capable of handling serious pressure.
Match Results: Hoffenheim
Latest news
OFI
❌ The match against Olympiacos was not entirely ideal in terms of squad fitness. Centre-back Dimitrios Nikolaou suffered an adductor injury and was forced off as early as the 13th minute, replaced by Krešimir Krizmanić. Christos Sielis was also not fully fit for the game. Both issues are a serious concern for OFI ahead of the match against the German club.
🔁 Update, 17 September, 4:29 UTC:
- Christos Sielis has been included in the squad for the match against Hoffenheim. The Cypriot missed the last three matches through injury, having started the season as a regular defensive starter with four appearances in August.
🔁 Update, 17 September, 11:15 UTC:
- Nikolaos Marinakis has not been included in the squad. The defender has been injured for more than a month and a half and has yet to play this season. Anastasios Chatzigiovanis and Athanasios Sitmalidis are also absent from the squad. The forward only recently joined OFI and has managed just 20 minutes against Olympiacos in the league, while the midfielder has played two Greek Cup matches this season.
Hoffenheim
❌ Alexander Prass has not recovered from a muscle injury. Koki Machida is also a doubt - the defender has returned to the squad after a fitness issue, but his involvement from the start is not guaranteed.
🔁 Update, 17 September, 4:33 UTC:
- Hoffenheim head coach Christian Ilzer has confirmed that Alexander Prass has recovered from his muscle injury. The midfielder has not played at all this season. Last season too, the Austrian was an option off the bench rather than a starter.
🟨 Yellow Cards Prediction
For OFI this is a historic match, so a high intensity in the duels will be hard to avoid. The hosts will have to defend for long stretches against a more technical side, which increases the likelihood of tactical fouls. Hoffenheim could also pick up a few bookings when breaking up OFI's counter-attacks. The second half should be particularly tense as the stakes of each moment rise. Prediction: Total Yellow Cards - Over 3.5.
⚽ Goals Prediction
OFI have looked fairly solid defensively in recent matches, keeping four consecutive clean sheets. Hoffenheim, meanwhile, have scored six goals in three Bundesliga rounds but conceded seven. The Germans will likely enjoy more possession and create chances, but OFI at home are capable of hitting back on the counter-attack. A both-teams-to-score outcome looks quite plausible. Prediction: Both Teams to Score - Yes. Odds - 1.84*.
🚩 Corners Prediction
Hoffenheim will likely look to take control from the off and sustain lengthy spells of possession-based attacking play. OFI will sit more compactly and look for space on the break. In that scenario, the German side should generate enough attacks to earn several corners, while the hosts could add their own set pieces in the second half, particularly if they find themselves behind. Prediction: Total Corners - Over 8.5 at 1.52*.
*Odds are indicative and may vary across different bookmakers.
⭐ Editor's Prediction
OFI come into this historic match in fine form, having just beaten Olympiacos away from home and riding a three-match winning run. Their home ground and the emotional factor of a first-ever Europa League league phase fixture could make life genuinely difficult for Hoffenheim.
The Germans have a stronger squad and considerably more experience at European level. After two defeats to start their Bundesliga campaign, Hoffenheim have also found some confidence with a win over Stuttgart. Their defence, though, is far from solid - seven goals conceded in three league rounds.
I'm therefore expecting a fairly open match in which both sides will have chances to score. Main bet: Total Goals - Over 2.5. Predicted score: 1-2 to the German club.
