Como vs Leipzig Prediction 10 September 2026
📢 A year ago, few would have believed that Como and RB Leipzig would meet in the opening round of the 2026/27 Champions League. Yet both clubs earned their place in Europe's premier club competition through their performances last season. For Como, the match will be their debut in European football altogether, making it a historic occasion for the club. The fixture has given Cesc Fàbregas's side the chance to begin their campaign at the Stadio Giuseppe Sinigaglia - but will home support be enough for a successful start?
🔁 This prediction is updated on matchday. Keep an eye on the Latest News section.
Head-to-Head
📊 Como and RB Leipzig have never previously met.

Como 1907 Team Overview
🔵 Como were one of the standout discoveries of last season. Cesc Fàbregas's young side played with real boldness, looking to dominate even against top clubs, and picked up points consistently. The Lariani finished fourth in Serie A and qualified for the Champions League for the first time in their history. Ahead of the new season, many expected a drop-off, assuming the club would struggle to cope with the demands of three competitions simultaneously - the league, the Coppa Italia and Europe.
⚪ The start of the new season has so far done nothing but disprove those concerns. Como have played three Serie A matches and taken seven points from a possible nine. In the opening round they drew with Udinese (1-1), then beat Napoli 2-1, and last weekend thrashed Genoa 4-1. In all three matches the Lariani looked the stronger side and outperformed their opponents across a number of key statistical categories. It is also worth noting that all three of those matches were played away from home. Their first home game of the season will be in the Champions League, so the Stadio Giuseppe Sinigaglia is sure to be packed.
Match Results: Como 1907

Leipzig Team Overview
🔴 RB Leipzig are no strangers to the Champions League, despite the club having been founded relatively recently, in 2009. The German side have already appeared in the group stage seven times, and in 2019/20 reached the semi-finals. Since 2019, Leipzig have missed out on the Champions League just once - last season, after finishing seventh in the 2024/25 Bundesliga. Now they are back in the competition, having come third in the German top flight.
⚪ Leipzig's start to the new season has been slightly less convincing than Como's. They comfortably beat Eintracht Trier in the DFB-Pokal as expected (6-0), then dealt with Borussia Mönchengladbach in the league without too much trouble (3-0). However, last weekend they were surprisingly beaten by Werder, 1-3, despite looking clearly the better side: 71% possession and 19 shots to Werder's 12. They were let down by their finishing. So Leipzig go into their first Champions League match of the season in a somewhat deflated mood.
Match Results: Leipzig
Latest news
Como 1907
❌ Como head into the match with the same injury concern as before: Jayden Addai continues to recover from an Achilles tendon injury.
🔁 Update - 10 September, 10:48 UTC:
- One of the main talking points in the Italian media on matchday has been who will start as Como's centre-forward in the club's debut Champions League match. La Gazzetta dello Sport believes Fabregas will drop Anastasios Douvikas - who has started all three of Como's official matches so far - in favour of Moise Kean, signed on loan from Fiorentina for €10 million.
Leipzig
❌ RB Leipzig have noticeably more problems with their squad. Castello Lukeba and Brajan Gruda are both doubts due to a muscle injury and a shin injury respectively. Rocco Reitz and Christoph Baumgartner are expected to return around the end of September, Rómulo is unavailable for approximately another one to two weeks with a knee injury, and Assan Ouédraogo will miss several weeks with a shoulder injury.
🔁 Update - 10 September, 05:40 UTC:
- Three RB Leipzig players whose fitness had been in doubt are now ready to play. According to Die Welt, Castello Lukeba, Romulo and Brajan Gruda all took part in training the day before the match. However, Sky Sports still expect El Aynaoui to take Gruda's place in the starting XI.
🔁 Update - 10 September, 10:43 UTC:
- According to RB Leipzig's press service, Assan Ouédraogo could be included in the squad for the match against Como. Despite earlier reports about his recovery timeline, the player returned to training ahead of schedule.
Predicted Lineups
📋 Predicted starting XI for Como: Butez - Couto, Ramón, Chalobah, Valle - Perrone, Da Cunha - Diao, Paz, Baturina - Douvikas.
📋 Predicted starting XI for RB Leipzig: Vandevoordt - Baku, Orbán, Estève, Raum - Seiwald, El Aynaoui, Banzuzi - Gomis, Nkunku, Nusa.
⚽️ Goals Prediction
Goals are a central feature of RB Leipzig matches. The German club are happy to push forward and at the same time allow opponents to create chances at their end. At least three goals have been scored in each of their last eight matches, a run that stretches back to the end of last season. Como have also had no problems in front of goal at the start of their Serie A campaign, so Total Goals - Over 2.5 at 1.65* is worth considering here.
🚩 Corners Prediction
Last season RB Leipzig were one of the leading clubs for corners won, averaging 5.3 per match. That trend has continued into the new season, and the Germans have actually been winning corners even more frequently: in all three of their official matches this term they have earned at least seven. RB Leipzig Team Total Corners - Over 3.5 at 2.00* looks a very interesting option as a result.
🟨 Yellow Cards Prediction
Como's matches at the start of the season have been fairly calm - no more than three yellow cards were shown in any of their three fixtures. Even against a high-profile opponent like Napoli, where a lot of physical play might have been expected, the referee produced just one booking. Total Yellow Cards - Under 3.5 is worth considering here.
🚀 Player Stat Bet
Nico Paz is Como's standout player. The Argentine had two very successful seasons before this one, and in last season's Serie A he registered 12 goals and 6 assists in 35 matches. He has carried that form into the new campaign and already got on the scoresheet against Genoa. Given his role in Como's attack, a bet on Nico Paz to Score at 2.80* seems a logical choice.
😱 Risky Bet
This meeting between Como and RB Leipzig could potentially be one of the highest-scoring matches in the opening round of the Champions League. The Italians play bold attacking football and create plenty of chances, while the German club are also very dangerous going forward. Between them the two sides have already scored 17 goals in six official matches this season, and neither has been particularly reliable defensively. So it may be worth taking a risk on Total Goals - Over 4.5 at 4.20*.
🎯 Reliable Bet
Como rarely fail to score - they have found the net in 10 of their last 11 matches. RB Leipzig, meanwhile, have had plenty of defensive problems away from home, conceding in 10 of their last 11 away fixtures. Como to Score at 1.11* is the pick here.
👀 If the Match Goes Against the Script
Although almost every indicator points towards an open and high-scoring game, the opposite scenario cannot be ruled out entirely. This is Como's first ever Champions League match and their debut in European competition altogether, so a degree of nerves is quite possible. The Italians may play more cautiously than usual, take fewer risks going forward and above all try not to spoil a historic evening with an early mistake. If that is how things unfold, Total Goals - Under 2.5 at 2.50* does not look like a crazy option.
*Odds are indicative and may vary across different bookmakers.
⭐ Editor's Prediction
Como are considered favourites for this match, and that assessment seems fair given their strong start. However, RB Leipzig have also been playing decent football, and the German club have considerably more experience on the European stage, so the hosts should not expect an easy ride. Given the quality both teams have shown in attack, our main bet is Both Teams to Score - Yes. Expected score: 2-1.
