Cardinals vs Cubs Prediction 29 July 2026
📡 The Cubs are in full control as their road trip gets underway. After a 7-3 win, the visitors racked up seven runs in the first two innings of the next game and cruised to a 10-2 victory. St. Louis suffered their third straight defeat, dropping below the .500 mark. In Game 3, Dustin May and Matthew Boyd are set to take the mound as starting pitchers.
Head-to-Head
📊 Chicago have claimed seven of the last 10 head-to-head matchups, while St. Louis have taken three. The Cubs have won the four most recent meetings and racked up 17 runs over the first two games of this series. The visitors' advantage isn’t down to a single big inning-they consistently put pressure on both the starting pitchers and the heart of the Cardinals' bullpen.
Head-to-head statistics Cardinals - Cubs

St. Louis Cardinals Team Overview
St. Louis sit at 53-54 and have seen their wild card hopes take a hit. On Tuesday, the hosts surrendered seven runs before the end of the second inning and never managed to claw their way back into the contest. Offensively, they were limited to just seven hits and only managed to drive in two runs. The team will need to improve not only their starting pitching but also make far better use of their opportunities on base, especially against a left-handed opponent.
Match Results: St. Louis Cardinals

Chicago Cubs Team Overview
Chicago improve their record to 61-46 and continue to impress on their road trip. In Game 2, the visitors racked up 17 hits, getting production from nearly every spot in the lineup. The Cubs aren’t relying solely on the long ball-they’re consistently putting runners on base and forcing the opposition to turn to their bullpen early. This current offensive form takes significant pressure off Boyd; he simply needs to keep the hosts from putting together a big inning.
Match Results: Chicago Cubs
⚾ Starting Pitchers
Dustin May gets the nod for St. Louis, entering the game with a 5-7 record, a 4.59 ERA, and 103 strikeouts. The right-hander has struggled to limit hard contact and now faces a red-hot lineup that has put up 17 runs over their last two games.
Matthew Boyd takes the mound for Chicago with a 6-1 record, a 3.81 ERA, and 55 strikeouts. While the lefty doesn’t match May in strikeout numbers, he’s shown far better command and consistently keeps his team in front on the scoreboard.
⭐ Editor’s Prediction
St. Louis remain a dangerous side at home and will be eager to respond after back-to-back heavy defeats. However, the Cubs hold a clear offensive edge and have taken seven of the last ten head-to-head meetings. Boyd has delivered a steadier season, while May is coming off a game where he allowed 17 hits. The visitors have shown more composure on the bases and have twice established early leads already. Even if scoring drops off, Chicago’s overall advantage should hold. Our pick: Chicago Cubs to win.
