Red Sox vs Cubs Prediction 25 September 2026
📡 With Sunday’s game rescheduled, Boston and Chicago kick off the finals with a doubleheader right from the start. For Game 1, the Cubs send Clay Holmes to the mound, while the hosts counter with Alec Gamboa. Chicago have just clinched a playoff spot after edging Miami 2-1, while Boston wrap up the week mired in an offensive slump-scoring just three runs over their last four games. This contrast in form could prove decisive in the opening matchup of the day.
Boston top the historic top ten, but the games from years past bear little resemblance to today's opening matchup of the doubleheader.
📊 Boston have claimed victory in six of their last ten meetings with the Cubs. However, that stretch spans multiple seasons and doesn’t accurately reflect the current rosters. These games have featured a wide range of outcomes-from blowouts like 17-4 and 10-4 to low-scoring affairs such as 3-0 and 4-2. As a result, the Red Sox’s historical edge matters less than current form and the unusual starting lineup set for Game 1.
Head-to-head statistics Red Sox - Cubs
The Red Sox head into a doubleheader having managed just three runs over their last four games.
The Red Sox are enduring a dismal week at the plate. Over their last four games, they’ve managed just 1, 2, 1, and 0 runs, and on Thursday against Cleveland, they recorded only two hits. In their past ten outings, Boston are hitting a mere .208 with a .607 OPS. Heading into a doubleheader, this slump is particularly problematic, as they’ll need to split their key players across two games in a single day.
Match Results: Boston Red Sox
The Cubs get a full start from Holmes as they face Gamboa’s spot start.
The Cubs have just punched their ticket to October with a 2-1 win over Miami. Their last three outings have been quiet offensively-scoring just two runs in each-but prior to that, Chicago put up nine, five, and eight runs. Over their last ten games, they’re 5-5, and on paper, their lineup packs a lot more punch than Boston’s. The opening game of this doubleheader offers a prime opportunity to capitalize on their starting pitching advantage.
Match Results: Chicago Cubs
⚾ Starting Pitchers
Clay Holmes takes the mound for the Cubs with a 4-4 record and a 2.39 ERA over 52.2 innings; his season-long ERA sits at 3.25. His most recent outing was a rough one-he allowed six earned runs in 5.1 innings-but prior to that, Holmes had limited opponents to no more than two earned runs in back-to-back starts. His main objective will be to regain his usual command and prevent Boston’s struggling offense from gaining any early momentum.
Alec Gamboa enters with a 1-0 record, an impressive 1.16 ERA, and a 1.06 WHIP, but he’s mostly been used in short stints throughout the season. Over his last five appearances, he hasn’t gone beyond 1.1 innings in any outing. This means Boston will likely have to lean heavily on their bullpen in the opening game of this doubleheader, with another full contest still to come later in the evening.
⭐ Editor’s Prediction
The historical head-to-head slightly favors Boston, and Holmes is coming off a shaky start-those are the main concerns here. However, the setup for Game 1 looks far more favorable for the Cubs. The Red Sox have managed just three runs over their last four games and now open the doubleheader with a pitcher who’s typically used for just a single inning. Chicago, on the other hand, will have the chance to face Boston’s bullpen early while sending out a true starter expected to cover the first five or six innings. In a doubleheader scenario, that difference in starting pitching depth could prove decisive. We’re backing a Chicago Cubs win in Game 1 of the doubleheader.
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Betting Tips: Boston Red Sox - Chicago Cubs
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