Dodgers vs Cubs Prediction 25 April 2026
📡 Saturday's game in Los Angeles is already underway following a thrilling start to the series. On Friday, Chicago took the first game with a 6-4 victory, as the Cubs staged a late comeback, setting an open tone for the series. For April 25, MLB and ESPN confirm the starting pitchers will be Colin Rea and Roki Sasaki, providing a solid basis not only from the score of the first game but also within the pitching context for a prediction leaning towards the over.
Head-to-Head
📊 In their last 10 head-to-head encounters, Chicago have claimed victory 6 times, while Los Angeles have won 4. This advantage is significant not just for the win-loss record but also in terms of totals. Within this sample, there have been scores like (10-4), (7-4), and (6-3), and now they’ve added Friday’s (6-4) to the mix. This pairing doesn’t require an unusual scenario for the over to hit.
Head-to-head statistics Dodgers - Cubs

Los Angeles Dodgers Team Overview
After a more defensive series against San Francisco, the hosts quickly shifted into a different rhythm. In the first game against the Cubs, the Dodgers scored four runs but allowed their opponents to claw back into the game during the late innings. For a team with a 17-8 record and a 9-3 home record, this doesn't seem like a systemic issue. However, heading into the next matchup, one key factor remains: Los Angeles' home offense is still potent enough to push for 4-5 runs, even if the opposing starting pitcher delivers a solid performance.
Match Results: Los Angeles Dodgers

Chicago Cubs Team Overview
The visitors are currently experiencing one of the strongest offensive stretches in the league. According to ESPN, heading into Saturday, the Cubs boast a 9-1 record in their last 10 games. Their 6-4 victory on Friday further underscored their ability to close out games against formidable opponents, not just with an initial burst but also by finishing strong. Meanwhile, Chicago do not appear to be a team reliant on one or two players; their roster is deep enough to contribute consistently to the scoreboard without depending on a single big inning.
Match Results: Chicago Cubs
⚾ Starting Pitchers
For the Los Angeles Dodgers, Roki Sasaki takes the mound. According to the official probable pitchers page for April 25, he holds a 0-2 record, with a 6.11 ERA, a 1.87 WHIP over 17.2 innings, allowing 21 hits and 4 home runs. This is a crucial detail for the total: despite Sasaki's reputation and talent, his current stats don't suggest he's a starter who can automatically shut down the Cubs' hot offense to just 1-2 runs.
The Chicago Cubs will hand the ball to Colin Rea. His stats on this date are a 3-0 record, a 3.00 ERA, a 1.04 WHIP over 24 innings, with 20 strikeouts and only 2 home runs allowed. While this is noticeably more precise than Sasaki's numbers, Rea doesn't seem like the type of starter expected to single-handedly keep the game low-scoring, especially on the road against the Dodgers' home lineup. For the hosts, scoring 3-4 runs before the late innings seems quite reasonable against such a profile.