Rockies vs Padres Prediction 22 April 2026

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    Colorado Rockies
    Colorado Rockies
    San Diego Padres
    San Diego Padres
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    📡 A new series kicks off in Denver after Colorado failed to extend their successful run against the Dodgers. On Monday, the Rockies fell to Los Angeles (3-12), and the Dodgers ultimately left Denver with a series win. For April 21, San Diego have confirmed Randy Vasquez as their starter, while the home team's starting pitcher remains unannounced at the time of checking, adding an element of uncertainty even at the preview stage.

    Head-to-Head

    📊 In recent head-to-head matchups, San Diego have typically been more confident (9-1), particularly in games where the starting duel doesn't drag the match into a low-scoring affair. However, in Denver, this pairing is traditionally risky, as even a cautious start in the early innings can quickly open up after the middle of the game.

    Head-to-head statistics Rockies - Padres

    48%
    82 Wins
    51%
    87 Wins
    29.07.26
    major league baseball
    San Diego Padres
    San Diego Padres
    Colorado Rockies
    Colorado Rockies
    3
    1
    0
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    3
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    29.07.26
    major league baseball
    San Diego Padres
    San Diego Padres
    Colorado Rockies
    Colorado Rockies
    8
    7
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    2
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    4
    0
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    1
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    2
    2
    1
    1
    1
    0
    23.04.26
    MLB
    Colorado Rockies
    Colorado Rockies
    San Diego Padres
    San Diego Padres
    8
    10
    1
    0
    4
    2
    0
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    1
    1
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    1
    1
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    1
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    1
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    5
    23.04.26
    MLB
    Colorado Rockies
    Colorado Rockies
    San Diego Padres
    San Diego Padres
    8
    3
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    1
    4
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    1
    0
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    1
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    1
    1
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    22.04.26
    MLB
    Colorado Rockies
    Colorado Rockies
    San Diego Padres
    San Diego Padres
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    1
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    0
    0
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    0
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    Colorado Rockies Team Overview

    Even after a heavy defeat to the Dodgers, Colorado have had a recent positive stretch. Before Monday's game, they secured back-to-back wins against the same Los Angeles team, and on Sunday, they scored nine runs against a formidable opponent. However, the 3-12 game served as a reminder of the hosts' vulnerabilities: when the starting lineup or defense falters, a series can quickly slip out of their grasp.

    Match Results: Colorado Rockies

    01.09.26
    major league baseball
    Colorado Rockies
    Colorado Rockies
    Baltimore Orioles
    Baltimore Orioles
    1
    2
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    0
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    0
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    1
    0
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    1
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    L
    30.08.26
    major league baseball
    Atlanta Braves
    Atlanta Braves
    Colorado Rockies
    Colorado Rockies
    3
    2
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    L
    29.08.26
    major league baseball
    Atlanta Braves
    Atlanta Braves
    Colorado Rockies
    Colorado Rockies
    2
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    L
    28.08.26
    major league baseball
    Atlanta Braves
    Atlanta Braves
    Colorado Rockies
    Colorado Rockies
    6
    4
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    3
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    3
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    0
    1
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    L
    27.08.26
    major league baseball
    Washington Nationals
    Washington Nationals
    Colorado Rockies
    Colorado Rockies
    7
    1
    2
    0
    0
    0
    0
    1
    1
    0
    1
    0
    0
    0
    0
    0
    3
    0
    L
    Empty
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    San Diego Padres Team Overview

    The Padres enter this series following a strong performance in Anaheim. According to Reuters and AP, the team secured victories in their last two games against the Angels with scores of 4-1 and 2-1. Michael King and Mason Miller were instrumental in shutting down the opponent, leaving little room for long-ball threats. This sets a crucial backdrop for their trip to Colorado, as San Diego arrives after a series where both their starting pitching and bullpen delivered effectively.

    Match Results: San Diego Padres

    31.08.26
    major league baseball
    Cincinnati Reds
    Cincinnati Reds
    San Diego Padres
    San Diego Padres
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    5
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    4
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    W
    30.08.26
    major league baseball
    Tampa Bay Rays
    Tampa Bay Rays
    San Diego Padres
    San Diego Padres
    5
    4
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    L
    29.08.26
    major league baseball
    Tampa Bay Rays
    Tampa Bay Rays
    San Diego Padres
    San Diego Padres
    7
    6
    1
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    1
    1
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    4
    3
    0
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    L
    28.08.26
    major league baseball
    Tampa Bay Rays
    Tampa Bay Rays
    San Diego Padres
    San Diego Padres
    9
    4
    0
    0
    0
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    1
    0
    5
    0
    1
    2
    1
    2
    1
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    L
    26.08.26
    major league baseball
    San Diego Padres
    San Diego Padres
    Pittsburgh Pirates
    Pittsburgh Pirates
    3
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    W
    Empty
    There are no events
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    ⚾ Starting Pitchers

    As of the latest update, the Colorado Rockies have yet to confirm their starting pitcher for April 21. Both MLB probable pitchers and ESPN list the hosts as undecided for this game. This uncertainty is significant for the Denver series, as it impacts bullpen strategy and early game scenarios.

    For the San Diego Padres, Randy Vasquez will take the mound. As of April 21, he holds a 1-0 record, with a 2.49 ERA, a 1.29 WHIP, and 25 strikeouts. Based on current stats, the visitors' start appears quite reliable, especially when compared to the uncertainty surrounding the hosts.

    ⭐ Editor’s Prediction

    Based on the current form of the teams and their recent performances, San Diego Padres are expected to dominate the Colorado Rockies even on the road. A suitable bet seems to be Padres' individual total over 5.5 - the team consistently delivers high-scoring games against Colorado and maintains a strong offensive form.

    San Diego Padres Total Over (5,5)
    Published: 21/04/2026, 07:52

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    Betting Tips: Colorado Rockies - San Diego Padres

    Colorado Rockies have lost:
    colorado-rockiessan-diego-padresin 9 of last 10 games against San Diego Padres (MLB).
    San Diego Padres have won:
    san-diego-padresin 10 of last 11 games (MLB).
    San Diego Padres Win
    MyBookie
    -143
    Colorado Rockies have scored under 6.5 runs:
    colorado-rockiessan-diego-padresin 10 of last 11 games against San Diego Padres.
    colorado-rockiessan-diego-padresin last 9 games against San Diego Padres (MLB).
    colorado-rockiesin 10 of last 11 games (MLB).
    Colorado Rockies Total Under (6,5)
    -286
    San Diego Padres have scored over 4.5 runs:
    colorado-rockiessan-diego-padresin last 6 games against Colorado Rockies (MLB).
    San Diego Padres Total Over (4,5)
    -238
    Under 10.5 runs scored:
    san-diego-padresin 10 of last 11 San Diego Padres away games.
    san-diego-padresin last 6 San Diego Padres away games (MLB).
    Total Under (10,5)
    +115
    View more facts