Guardians vs Cubs Prediction 3 April 2026

Details
The main thing
    Cleveland Gardians
    Cleveland Gardians
    Chicago Cubs
    Chicago Cubs
    4
    1
    0
    0
    0
    0
    1
    0
    3
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    -
    0
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    The Guardians' home opener in Cleveland adds significant weight to the matchup. Reuters confirms the starting pitchers as Joey Cantillo and Cade Horton, while noting that Cleveland returns home after a strong road stretch against the Seattle Mariners and Los Angeles Dodgers. Chicago's form is also noteworthy: the Cubs just clinched a series against the Los Angeles Angels and have leveled their record. This is precisely the kind of game where the starting pitching duel could be decisive within the first five innings.

    Head-to-Head

    📊 In their last ten head-to-head matchups, the teams have an even split of 5-5. However, recent trends favor Chicago: in July 2025, the Cubs swept Cleveland at home with three consecutive victories (5-2, 5-4, and 1-0). This matchup also leans towards the under, with six of the last ten games hitting the under, which aligns well with the current starting duel.

    H2H Stats Matches and Previous Teams Results

    42%
    19 Wins
    51%
    23 Wins
    05.04.26
    MLB
    Cleveland Gardians
    Cleveland Gardians
    Chicago Cubs
    Chicago Cubs
    6
    5
    0
    0
    0
    0
    0
    1
    0
    0
    0
    0
    3
    2
    0
    0
    3
    1
    05.04.26
    MLB
    Cleveland Gardians
    Cleveland Gardians
    Chicago Cubs
    Chicago Cubs
    0
    1
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    1
    0
    0
    03.04.26
    MLB
    Cleveland Gardians
    Cleveland Gardians
    Chicago Cubs
    Chicago Cubs
    4
    1
    0
    0
    0
    0
    0
    1
    0
    0
    1
    0
    0
    0
    3
    0
    0
    0
    04.07.25
    MLB
    Chicago Cubs
    Chicago Cubs
    Cleveland Gardians
    Cleveland Gardians
    1
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    1
    0
    03.07.25
    MLB
    Chicago Cubs
    Chicago Cubs
    Cleveland Gardians
    Cleveland Gardians
    5
    4
    0
    0
    0
    2
    2
    1
    3
    0
    0
    0
    0
    0
    0
    0
    0
    0
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    Cleveland Gardians Team Overview

    The Guardians earn respect just for their challenging start to the season. Reuters highlights that they kicked off the year with a seven-game road trip against the Seattle Mariners and Los Angeles Dodgers. They split the series with the Mariners and then clinched two out of three games against Los Angeles. Their latest victory (4-1) is particularly impressive: Gavin Williams struck out 10, while José Ramírez and Gabriel Arias each hit a home run, and the team overall looked very composed against one of the league's most formidable lineups. Returning home after such a trip is a significant emotional boost, and in their home opener, Cleveland certainly won't be a passive opponent.

    Match Results: Cleveland Gardians

    20.06.26
    MLB
    Houston Astros
    Houston Astros
    Cleveland Gardians
    Cleveland Gardians
    9
    3
    1
    0
    0
    0
    1
    3
    0
    0
    0
    0
    3
    0
    2
    0
    2
    0
    L
    18.06.26
    MLB
    Milwaukee Brewers
    Milwaukee Brewers
    Cleveland Gardians
    Cleveland Gardians
    2
    4
    0
    0
    1
    0
    0
    1
    1
    0
    0
    0
    0
    1
    0
    2
    0
    0
    0
    0
    W
    17.06.26
    MLB
    Milwaukee Brewers
    Milwaukee Brewers
    Cleveland Gardians
    Cleveland Gardians
    9
    4
    3
    0
    2
    0
    0
    0
    2
    4
    0
    0
    0
    0
    0
    0
    2
    0
    L
    16.06.26
    MLB
    Milwaukee Brewers
    Milwaukee Brewers
    Cleveland Gardians
    Cleveland Gardians
    2
    1
    0
    0
    0
    0
    0
    0
    1
    0
    0
    0
    0
    0
    1
    1
    0
    0
    L
    13.06.26
    MLB
    Cleveland Gardians
    Cleveland Gardians
    Detroit Tigers
    Detroit Tigers
    3
    1
    0
    1
    1
    0
    2
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    0
    W
    Empty
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    Chicago Cubs Team Overview

    Chicago heads to Cleveland following a valuable 6-2 victory over the Angels. Reuters highlighted Nico Hoerner's three hits, a strong performance from Matt Shaw, and an especially crucial bounce-back start from Matthew Boyd, who struck out 10 batters. For the Cubs, this is an important indicator as their season has been inconsistent, with strong games mixed with lackluster stretches. However, they approach the trip to Cleveland feeling that the series against Los Angeles has corrected some issues. An additional positive is the confirmed start for Cade Horton, who has already shown he can quickly adapt at this level.

    Match Results: Chicago Cubs

    19.06.26
    MLB
    Chicago Cubs
    Chicago Cubs
    Toronto Blue Jays
    Toronto Blue Jays
    16
    2
    7
    0
    0
    0
    0
    1
    0
    0
    0
    0
    4
    1
    5
    0
    0
    0
    W
    18.06.26
    MLB
    Chicago Cubs
    Chicago Cubs
    Colorado Rockies
    Colorado Rockies
    8
    6
    0
    0
    7
    0
    0
    1
    1
    0
    0
    1
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    0
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    3
    W
    17.06.26
    MLB
    Chicago Cubs
    Chicago Cubs
    Colorado Rockies
    Colorado Rockies
    2
    5
    1
    0
    1
    0
    0
    0
    0
    3
    0
    2
    0
    0
    0
    0
    0
    0
    0
    0
    L
    16.06.26
    MLB
    Chicago Cubs
    Chicago Cubs
    Colorado Rockies
    Colorado Rockies
    5
    4
    1
    0
    0
    0
    0
    0
    0
    0
    0
    0
    1
    1
    0
    0
    1
    3
    2
    0
    W
    14.06.26
    MLB
    San Francisco Giants
    San Francisco Giants
    Chicago Cubs
    Chicago Cubs
    5
    1
    0
    0
    0
    0
    0
    0
    0
    0
    3
    0
    0
    0
    1
    0
    1
    1
    L
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    ⚾️ Starting Pitchers

    The Guardians are sending Joey Cantillo to the mound, who carries a 4.91 ERA. The head-to-head history adds an interesting angle here: back in July 2025, Horton faced off against Cleveland and delivered seven scoreless innings in a 1-0 victory.

    The Cubs will have Cade Horton pitching, who holds a 1-0 record with a 2.84 ERA, while Cantillo didn't make it past the fourth inning in that matchup. While it's not possible to directly compare that game to the current one, Horton appears to be the slightly more reliable option based on their profiles as starting pitchers.

    Editor's Prediction

    This is a high-quality and rather finely balanced matchup. Cleveland are playing at home following a challenging road trip against top-tier opponents, which could give them an emotional boost. However, from a purely baseball perspective, Chicago have several compelling arguments: Horton has already proven capable of containing this lineup, last season's head-to-head series favored the Cubs, and after their victory over the Angels, the team embarks on this trip with a calmer mindset. I wouldn't expect a high-scoring affair; both the history of their encounters and the starting pitchers suggest a tight, low-scoring game. Therefore, our pick here is a Chicago Cubs victory in what promises to be a hard-fought contest.
    Our choice
    Chicago Cubs Win at odds of -115*
    *The odds are relevant for the time of publication (3 April 2026, 07:04)

    Betting Tips: Cleveland Gardians - Chicago Cubs

    Cleveland Gardians have lost:
    cleveland-indianschicago-cubsin last 7 games against Chicago Cubs.
    Chicago Cubs Win
    Bovada
    -112
    Chicago Cubs have lost:
    cleveland-indianschicago-cubsin last 5 away games against Cleveland Gardians (MLB).
    Cleveland Gardians Win
    MyBookie
    +155
    Over 6.5 runs scored:
    cleveland-indianschicago-cubsin 7 of last 8 Cleveland Gardians games against Chicago Cubs.
    cleveland-indiansin 13 of last 14 Cleveland Gardians home games.
    chicago-cubsin last 5 Chicago Cubs away games.
    Total Over (6,5)
    MyBookie
    -133
    Chicago Cubs have scored over 3.5 runs:
    cleveland-indianschicago-cubsin 6 of last 7 games against Cleveland Gardians.
    Chicago Cubs Total Over (3,5)
    -137
    View more facts