Los Angeles Rams vs New York Giants Prediction 22 September 2026
✨ In Week 2 of the NFL regular season, the Los Angeles Rams host the New York Giants at SoFi Stadium in Inglewood. The Rams are eager to bounce back in front of their home crowd after a disappointing season opener in Australia. Meanwhile, the Giants arrive in California riding high on confidence following a convincing home win over Dallas.
New York’s edge and tight finishes: head-to-head history
📊 In the head-to-head history between these franchises, the Giants hold the upper hand, claiming six wins in their last ten encounters, while the Californians have come out on top four times. Their most recent meeting, back in December 2023, delivered real drama for the fans and saw the Los Angeles Rams edge out a narrow 26-25 victory.
Head-to-head statistics Los Angeles Rams - New York Giants

Los Angeles Rams: Home Recovery and the Search for Balance
The Los Angeles Rams stumbled out of the gate in the regular season, suffering a heavy 27-7 defeat to San Francisco in Melbourne, Australia. Head coach Sean McVay is counting on a return to familiar territory at home to help his side regain their rhythm after a grueling long-haul trip. Offensively, the Californians plan to get star receivers Puka Nacua and Davante Adams more involved, pairing their aerial threat with the ground game of Kyren Williams and Blake Corum. Defensively, much hinges on the fitness of their key players, as uncertainty surrounding Aaron Donald and Myles Garrett adds extra pressure to the hosts’ lineup. Back on home turf, the Rams will aim to seize the initiative early and prevent their opponents from dictating the tempo and controlling possession.
Match Results: Los Angeles Rams

New York Giants: A Confident Start and Physical Dominance
The New York Giants impressed in their season opener, confidently defeating the Dallas Cowboys 28-20 under new head coach John Harbaugh. Young quarterback Jaxson Dart displayed impressive passing accuracy, tossing three touchdowns and reading defensive schemes with poise. Running back Cam Skattebo and tight end Isaiah Likely have both hit top form, emerging as key options for the Giants during long, methodical drives. The visitors rely on a power running game and disciplined play from their blocking unit, consistently controlling possession and limiting opponents’ opportunities. As they travel to Inglewood, the Giants will look to dictate a physical tempo and put California’s defense under sustained pressure with hard-nosed, contact-heavy football.