Buffalo Bills vs New England Patriots Prediction 4 October 2026
🔥 The Buffalo Bills and New England Patriots are set to clash at Highmark Stadium in Orchard Park as part of Week 4 in the new NFL season. The hosts come into this matchup boasting an impressive run-Buffalo have claimed victory in eight of their last ten games, averaging 30.2 points per contest. The Patriots, meanwhile, have secured seven wins over that same stretch, but their offensive output lags behind, with an average of just 21.1 points per game.
Head-to-head statistics Buffalo Bills - New England Patriots

Buffalo Bills Team Overview
The Buffalo Bills are showing impressive early-season form, going unbeaten through their first three games while averaging 33.7 points per contest. However, their defense has also been leaky, conceding an average of 26 points per game. Looking at a broader sample of the last ten outings, Buffalo have claimed eight wins and suffered just two defeats, with their average points allowed dropping to 24.1. A key trend to highlight is their offensive firepower: the Bills have scored over 27.5 points in six of their last seven matchups, underlining their potent attack ahead of this home fixture.
Match Results: Buffalo Bills

New England Patriots Team Overview
The New England Patriots have struggled with consistency, managing just one win in their first three games of the season while averaging only 12 points scored and conceding 17 per contest. Over their last ten outings, the Patriots have looked more solid with seven victories, but even then, their offense has been capped at an average of just 21.1 points. What's particularly interesting is the contrast between their season-long stats and their recent form: while New England’s offensive output for the season is notably lower (12 points compared to their ten-game average), their defense remains steady, allowing around 15 points per game. One clear trend stands out-Patriots’ road games consistently hit the under, with the total going under the line in 22 of their last 23 away fixtures.